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result sql = [Relationships of human laryngeal squamous cell carcinomas with the expression of VEGF-C and VEGFR-3].

[Relationships of human laryngeal squamous cell carcinomas with the expression of VEGF-C and VEGFR-3].

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char = ;code = 32
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char = E;code = 69
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char = F;code = 70
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char = e;code = 101
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char = a;code = 97
char = t;code = 116
char = e;code = 101
char = d;code = 100
char = ;code = 32
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char = t;code = 116
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char = ;code = 32
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char = ;code = 32
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char = .;code = 46
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char = t;code = 116
char = s;code = 115
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char = s;code = 115
char = u;code = 117
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char = g;code = 103
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char = s;code = 115
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char = l;code = 108
char = ;code = 32
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char = r;code = 114
char = ;code = 32
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char = e;code = 101
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char = s;code = 115
char = ;code = 32
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char = ;code = 32
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char = n;code = 110
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char = i;code = 105
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char = o;code = 111
char = r;code = 114
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = p;code = 112
char = r;code = 114
char = o;code = 111
char = g;code = 103
char = n;code = 110
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char = t;code = 116
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char = c;code = 99
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char = g;code = 103
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char = n;code = 110
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char = e;code = 101
char = a;code = 97
char = l;code = 108
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = L;code = 76
char = S;code = 83
char = C;code = 67
char = C;code = 67
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char = <;code = 60
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char = /;code = 47
char = >;code = 62
result sql = In order to detect the relationships of human laryngeal squamous cell carcinoma (LSCC) with the expression of Vascular Endothelial Growth Factor C (VEGF-C) and Vascular Endothelial Growth Factor Receptor-3 (VEGFR-3), we examined the level of VEGF-C and VEGFR-3 gene expression in the samples from 30 cases of normal laryngeal mucosa tissue (NLM), primary laryngeal carcinoma (PLC) and cervical lymph node (CLN) by using reverse transcription polymerase chain reaction (RT-PCR). The protein levels of VEGF-C and VEGFR-3 expression were also determined by Western blotting in 10 cases of NLM, PLC, CLN,respectively. We found that in the samples from the same patient, the VEGF-C and VEGFR-3 expression level is different among normal laryngeal mucosa tissue, primary laryngeal carcinoma and cervical lymph node. In primary laryngeal carcinoma, the level of VEGF-C and VEGFR-3 expression was significantly higher in lymph node positive group than in lymph node negative group, and this difference was the associated with the histological grade of differentiation (P < 0.05). The expression levels of VEGF-C and VEGFR-3 were not associated with age, sex, site and T stage (P > 0.5). These results suggest that there is a close relationship of LSCC with VEGF-C/VEGFR-3; and VEGF-C/VEGFR-3 may have the potential for use as an indicator with prognostic significance in dealing with LSCC.

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