|
|
char = T;code = 84
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result sql = Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation.
Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation.char = T;code = 84
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char = s;code = 115
char = o;code = 111
char = r;code = 114
char = d;code = 100
char = e;code = 101
char = r;code = 114
char = s;code = 115
char = ,;code = 44
char = ;code = 32
char = s;code = 115
char = u;code = 117
char = c;code = 99
char = h;code = 104
char = ;code = 32
char = a;code = 97
char = s;code = 115
char = ;code = 32
char = d;code = 100
char = y;code = 121
char = s;code = 115
char = l;code = 108
char = i;code = 105
char = p;code = 112
char = i;code = 105
char = d;code = 100
char = e;code = 101
char = m;code = 109
char = i;code = 105
char = a;code = 97
char = s;code = 115
char = ,;code = 44
char = ;code = 32
char = o;code = 111
char = b;code = 98
char = e;code = 101
char = s;code = 115
char = i;code = 105
char = t;code = 116
char = y;code = 121
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = d;code = 100
char = i;code = 105
char = a;code = 97
char = b;code = 98
char = e;code = 101
char = t;code = 116
char = e;code = 101
char = s;code = 115
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
result sql = Thyroid hormone influences diverse metabolic pathways important in lipid and glucose metabolism, lipolysis and regulation of body weight. Recently, it has been recognized that thyroid hormone receptor interacts with transcription factors that predominantly respond to nutrient signals including the peroxisome proliferator-activated receptors, liver X receptor and others. CROSSTALK BETWEEN THYROID HORMONE SIGNALING AND THESE NUTRIENT RESPONSIVE FACTORS OCCURS THROUGH A VARIETY OF MECHANISMS: competition for retinoid X receptor heterodimer partners, DNA binding sites and transcriptional cofactors. This review focuses on the mechanisms of interaction of thyroid hormone signaling with other metabolic pathways and the importance of understanding these interactions to develop therapeutic agents for treatment of metabolic disorders, such as dyslipidemias, obesity and diabetes.
char = h;code = 104
char = y;code = 121
char = r;code = 114
char = o;code = 111
char = i;code = 105
char = d;code = 100
char = ;code = 32
char = h;code = 104
char = o;code = 111
char = r;code = 114
char = m;code = 109
char = o;code = 111
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = c;code = 99
char = r;code = 114
char = o;code = 111
char = s;code = 115
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = l;code = 108
char = k;code = 107
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = n;code = 110
char = u;code = 117
char = c;code = 99
char = l;code = 108
char = e;code = 101
char = a;code = 97
char = r;code = 114
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = c;code = 99
char = e;code = 101
char = p;code = 112
char = t;code = 116
char = o;code = 111
char = r;code = 114
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = g;code = 103
char = n;code = 110
char = a;code = 97
char = l;code = 108
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = m;code = 109
char = e;code = 101
char = t;code = 116
char = a;code = 97
char = b;code = 98
char = o;code = 111
char = l;code = 108
char = i;code = 105
char = c;code = 99
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = g;code = 103
char = u;code = 117
char = l;code = 108
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = .;code = 46
result sql = Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation.
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char = y;code = 121
char = r;code = 114
char = o;code = 111
char = i;code = 105
char = d;code = 100
char = ;code = 32
char = h;code = 104
char = o;code = 111
char = r;code = 114
char = m;code = 109
char = o;code = 111
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = f;code = 102
char = l;code = 108
char = u;code = 117
char = e;code = 101
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = d;code = 100
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = r;code = 114
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = m;code = 109
char = e;code = 101
char = t;code = 116
char = a;code = 97
char = b;code = 98
char = o;code = 111
char = l;code = 108
char = i;code = 105
char = c;code = 99
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = t;code = 116
char = h;code = 104
char = w;code = 119
char = a;code = 97
char = y;code = 121
char = s;code = 115
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char = i;code = 105
char = m;code = 109
char = p;code = 112
char = o;code = 111
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char = t;code = 116
char = a;code = 97
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char = t;code = 116
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char = p;code = 112
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char = d;code = 100
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char = g;code = 103
char = l;code = 108
char = u;code = 117
char = c;code = 99
char = o;code = 111
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = m;code = 109
char = e;code = 101
char = t;code = 116
char = a;code = 97
char = b;code = 98
char = o;code = 111
char = l;code = 108
char = i;code = 105
char = s;code = 115
char = m;code = 109
char = ,;code = 44
char = ;code = 32
char = l;code = 108
char = i;code = 105
char = p;code = 112
char = o;code = 111
char = l;code = 108
char = y;code = 121
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char = i;code = 105
char = s;code = 115
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = r;code = 114
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char = g;code = 103
char = u;code = 117
char = l;code = 108
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = b;code = 98
char = o;code = 111
char = d;code = 100
char = y;code = 121
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char = w;code = 119
char = e;code = 101
char = i;code = 105
char = g;code = 103
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char = t;code = 116
char = .;code = 46
char = ;code = 32
char = R;code = 82
char = e;code = 101
char = c;code = 99
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char = y;code = 121
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char = i;code = 105
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char = h;code = 104
char = a;code = 97
char = s;code = 115
char = ;code = 32
char = b;code = 98
char = e;code = 101
char = e;code = 101
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char = ;code = 32
char = r;code = 114
char = e;code = 101
char = c;code = 99
char = o;code = 111
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char = n;code = 110
char = i;code = 105
char = z;code = 122
char = e;code = 101
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char = ;code = 32
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char = a;code = 97
char = t;code = 116
char = ;code = 32
char = t;code = 116
char = h;code = 104
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char = d;code = 100
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char = h;code = 104
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char = m;code = 109
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char = c;code = 99
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char = e;code = 101
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char = a;code = 97
char = c;code = 99
char = t;code = 116
char = s;code = 115
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char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = t;code = 116
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char = a;code = 97
char = n;code = 110
char = s;code = 115
char = c;code = 99
char = r;code = 114
char = i;code = 105
char = p;code = 112
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
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char = a;code = 97
char = c;code = 99
char = t;code = 116
char = o;code = 111
char = r;code = 114
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char = o;code = 111
char = ;code = 32
char = n;code = 110
char = u;code = 117
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = e;code = 101
char = n;code = 110
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char = g;code = 103
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char = a;code = 97
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char = l;code = 108
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char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = t;code = 116
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char = e;code = 101
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char = e;code = 101
char = r;code = 114
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char = x;code = 120
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char = m;code = 109
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char = p;code = 112
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char = o;code = 111
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char = i;code = 105
char = f;code = 102
char = e;code = 101
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char = a;code = 97
char = t;code = 116
char = o;code = 111
char = r;code = 114
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char = c;code = 99
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char = v;code = 118
char = a;code = 97
char = t;code = 116
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char = d;code = 100
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char = e;code = 101
char = c;code = 99
char = e;code = 101
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char = t;code = 116
char = o;code = 111
char = r;code = 114
char = s;code = 115
char = ,;code = 44
char = ;code = 32
char = l;code = 108
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = X;code = 88
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = c;code = 99
char = e;code = 101
char = p;code = 112
char = t;code = 116
char = o;code = 111
char = r;code = 114
char = ;code = 32
char = a;code = 97
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char = d;code = 100
char = ;code = 32
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char = h;code = 104
char = e;code = 101
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char = s;code = 115
char = .;code = 46
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char = <;code = 60
char = b;code = 98
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char = C;code = 67
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char = S;code = 83
char = S;code = 83
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char = A;code = 65
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char = K;code = 75
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char = E;code = 69
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char = W;code = 87
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char = E;code = 69
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char = T;code = 84
char = H;code = 72
char = Y;code = 89
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char = I;code = 73
char = D;code = 68
char = ;code = 32
char = H;code = 72
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char = M;code = 77
char = O;code = 79
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char = E;code = 69
char = ;code = 32
char = S;code = 83
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char = G;code = 71
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char = A;code = 65
char = L;code = 76
char = I;code = 73
char = N;code = 78
char = G;code = 71
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char = A;code = 65
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char = V;code = 86
char = A;code = 65
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char = I;code = 73
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char = C;code = 67
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char = S;code = 83
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char = b;code = 98
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char = t;code = 116
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char = d;code = 100
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char = c;code = 99
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char = b;code = 98
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char = t;code = 116
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char = o;code = 111
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char = y;code = 121
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char = d;code = 100
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char = h;code = 104
char = o;code = 111
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char = m;code = 109
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char = e;code = 101
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char = m;code = 109
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char = i;code = 105
char = c;code = 99
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char = a;code = 97
char = t;code = 116
char = h;code = 104
char = w;code = 119
char = a;code = 97
char = y;code = 121
char = s;code = 115
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char = h;code = 104
char = e;code = 101
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char = i;code = 105
char = m;code = 109
char = p;code = 112
char = o;code = 111
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char = t;code = 116
char = a;code = 97
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char = c;code = 99
char = e;code = 101
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char = o;code = 111
char = f;code = 102
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char = u;code = 117
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char = a;code = 97
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char = d;code = 100
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = t;code = 116
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result sql = Thyroid hormone influences diverse metabolic pathways important in lipid and glucose metabolism, lipolysis and regulation of body weight. Recently, it has been recognized that thyroid hormone receptor interacts with transcription factors that predominantly respond to nutrient signals including the peroxisome proliferator-activated receptors, liver X receptor and others. CROSSTALK BETWEEN THYROID HORMONE SIGNALING AND THESE NUTRIENT RESPONSIVE FACTORS OCCURS THROUGH A VARIETY OF MECHANISMS: competition for retinoid X receptor heterodimer partners, DNA binding sites and transcriptional cofactors. This review focuses on the mechanisms of interaction of thyroid hormone signaling with other metabolic pathways and the importance of understanding these interactions to develop therapeutic agents for treatment of metabolic disorders, such as dyslipidemias, obesity and diabetes.
Publication: Trends Endocrinol. Metab. 2010 Mar ;21(3)::166-73. :doi: 10.1016/j.tem.2009.11.004.
Publication Date: 2010 Mar
Study Author(s): Liu, Yan-Yun;Brent, Gregory A;
Institution: Molecular Endocrinology Laboratory, VA Greater Los Angeles Healthcare System, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90073, USA.
Shortcut link to this study:
Publication Date: 2010 Mar
Study Author(s): Liu, Yan-Yun;Brent, Gregory A;
Institution: Molecular Endocrinology Laboratory, VA Greater Los Angeles Healthcare System, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90073, USA.
Shortcut link to this study:
Thyroid hormone influences diverse metabolic pathways important in lipid and glucose metabolism, lipolysis and regulation of body weight. Recently, it has been recognized that thyroid hormone receptor interacts with transcription factors that predominantly respond to nutrient signals including the peroxisome proliferator-activated receptors, liver X receptor and others. CROSSTALK BETWEEN THYROID HORMONE SIGNALING AND THESE NUTRIENT RESPONSIVE FACTORS OCCURS THROUGH A VARIETY OF MECHANISMS: competition for retinoid X receptor heterodimer partners, DNA binding sites and transcriptional cofactors. This review focuses on the mechanisms of interaction of thyroid hormone signaling with other metabolic pathways and the importance of understanding these interactions to develop therapeutic agents for treatment of metabolic disorders, such as dyslipidemias, obesity and diabetes.
PMID: 20015660
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