|
|
char = A;code = 65
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char = u;code = 117
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char = o;code = 111
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char = l;code = 108
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char = l;code = 108
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char = r;code = 114
char = i;code = 105
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char = o;code = 111
char = m;code = 109
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char = c;code = 99
char = h;code = 104
char = .;code = 46
result sql = A functional extracellular matrix biomaterial derived from ovine forestomach.
A functional extracellular matrix biomaterial derived from ovine forestomach.char = E;code = 69
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char = t;code = 116
char = r;code = 114
char = a;code = 97
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char = a;code = 97
char = t;code = 116
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char = i;code = 105
char = x;code = 120
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char = (;code = 40
char = E;code = 69
char = C;code = 67
char = M;code = 77
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char = a;code = 97
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char = o;code = 111
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char = v;code = 118
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char = a;code = 97
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char = t;code = 116
char = a;code = 97
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char = p;code = 112
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char = c;code = 99
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char = ;code = 32
char = m;code = 109
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char = ;code = 32
char = I;code = 73
char = n;code = 110
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
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char = e;code = 101
char = a;code = 97
char = r;code = 114
char = c;code = 99
char = h;code = 104
char = ;code = 32
char = f;code = 102
char = o;code = 111
char = r;code = 114
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char = b;code = 98
char = i;code = 105
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char = m;code = 109
char = a;code = 97
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char = e;code = 101
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char = a;code = 97
char = l;code = 108
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char = w;code = 119
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char = h;code = 104
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char = f;code = 102
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char = c;code = 99
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char = m;code = 109
char = a;code = 97
char = t;code = 116
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char = (;code = 40
char = O;code = 79
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char = M;code = 77
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char = E;code = 69
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char = O;code = 79
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char = a;code = 97
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char = m;code = 109
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char = s;code = 115
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char = f;code = 102
char = ;code = 32
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char = e;code = 101
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char = E;code = 69
char = C;code = 67
char = M;code = 77
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char = ;code = 32
char = t;code = 116
char = i;code = 105
char = s;code = 115
char = s;code = 115
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char = e;code = 101
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char = d;code = 100
char = e;code = 101
char = l;code = 108
char = a;code = 97
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
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char = .;code = 46
char = ;code = 32
char = O;code = 79
char = F;code = 70
char = M;code = 77
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char = p;code = 112
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result sql = Extracellular matrix (ECM) based biomaterials have an established place as medical devices for wound healing and tissue regeneration. In the search for biomaterials we have identified ovine forestomach matrix (OFM), a thick, large format ECM which is biochemically diverse and biologically functional. OFM was purified using an osmotic process that was shown to reduce the cellularity of the ECM and aid tissue delamination. OFM produced using this technique was shown to retain residual basement membrane components, as evidence by the presence of laminin and collagen IV. The collagenous microarchitecture of OFM retained many components of native ECM including fibronectin, glycosaminoglycans, elastin and fibroblast growth factor basic. OFM was non-toxic to mammalian cells and supported fibroblast and keratinocyte migration, differentiation and infiltration. OFM is a culturally acceptable alternative to current collagen-based biomaterials and has immediate clinical applications in wound healing and tissue regeneration.
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result sql = A functional extracellular matrix biomaterial derived from ovine forestomach.
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result sql = Extracellular matrix (ECM) based biomaterials have an established place as medical devices for wound healing and tissue regeneration. In the search for biomaterials we have identified ovine forestomach matrix (OFM), a thick, large format ECM which is biochemically diverse and biologically functional. OFM was purified using an osmotic process that was shown to reduce the cellularity of the ECM and aid tissue delamination. OFM produced using this technique was shown to retain residual basement membrane components, as evidence by the presence of laminin and collagen IV. The collagenous microarchitecture of OFM retained many components of native ECM including fibronectin, glycosaminoglycans, elastin and fibroblast growth factor basic. OFM was non-toxic to mammalian cells and supported fibroblast and keratinocyte migration, differentiation and infiltration. OFM is a culturally acceptable alternative to current collagen-based biomaterials and has immediate clinical applications in wound healing and tissue regeneration.
Publication: Biomaterials 2010 Jun ;31(16)::4517-29. :doi: 10.1016/j.biomaterials.2010.02.025.
Publication Date: 2010 Jun
Study Author(s): Lun, Stan;Irvine, Sharleen M;Johnson, Keryn D;Fisher, Neil J;Floden, Evan W;Negron, Leonardo;Dempsey, Sandi G;McLaughlin, Rene J;Vasudevamurthy, Madhusudan;Ward, Brian R;May, Barnaby C H;
Institution: Mesynthes Limited, Lower Hutt 5040, New Zealand.
Shortcut link to this study:
Publication Date: 2010 Jun
Study Author(s): Lun, Stan;Irvine, Sharleen M;Johnson, Keryn D;Fisher, Neil J;Floden, Evan W;Negron, Leonardo;Dempsey, Sandi G;McLaughlin, Rene J;Vasudevamurthy, Madhusudan;Ward, Brian R;May, Barnaby C H;
Institution: Mesynthes Limited, Lower Hutt 5040, New Zealand.
Shortcut link to this study:
Extracellular matrix (ECM) based biomaterials have an established place as medical devices for wound healing and tissue regeneration. In the search for biomaterials we have identified ovine forestomach matrix (OFM), a thick, large format ECM which is biochemically diverse and biologically functional. OFM was purified using an osmotic process that was shown to reduce the cellularity of the ECM and aid tissue delamination. OFM produced using this technique was shown to retain residual basement membrane components, as evidence by the presence of laminin and collagen IV. The collagenous microarchitecture of OFM retained many components of native ECM including fibronectin, glycosaminoglycans, elastin and fibroblast growth factor basic. OFM was non-toxic to mammalian cells and supported fibroblast and keratinocyte migration, differentiation and infiltration. OFM is a culturally acceptable alternative to current collagen-based biomaterials and has immediate clinical applications in wound healing and tissue regeneration.
PMID: 20226520
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