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result sql = Serum 25-hydroxyvitamin D levels in patients with cutaneous lupus erythematosus in a Mediterranean region.
Serum 25-hydroxyvitamin D levels in patients with cutaneous lupus erythematosus in a Mediterranean region.
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char = g;code = 103
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char = c;code = 99
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char = y;code = 121
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char = i;code = 105
char = t;code = 116
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char = i;code = 105
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char = D;code = 68
char = ;code = 32
char = (;code = 40
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char = d;code = 100
char = s;code = 115
char = ;code = 32
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char = i;code = 105
char = o;code = 111
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char = .;code = 46
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char = 5;code = 53
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char = ;code = 32
char = c;code = 99
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char = i;code = 105
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char = ;code = 32
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char = 1;code = 49
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char = .;code = 46
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char = .;code = 46
char = ;code = 32
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char = h;code = 104
char = e;code = 101
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char = u;code = 117
char = l;code = 108
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char = d;code = 100
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char = u;code = 117
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char = t;code = 116
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char = t;code = 116
char = a;code = 97
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char = ;code = 32
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char = ;code = 32
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char = e;code = 101
char = ;code = 32
char = p;code = 112
char = r;code = 114
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char = d;code = 100
char = ;code = 32
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char = e;code = 101
char = a;code = 97
char = t;code = 116
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = C;code = 67
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char = E;code = 69
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char = ;code = 32
char = L;code = 76
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char = s;code = 115
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char = 1;code = 49
char = 0;code = 48
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char = ;code = 32
char = 1;code = 49
char = 9;code = 57
char = ,;code = 44
char = ;code = 32
char = 8;code = 56
char = 1;code = 49
char = 0;code = 48
char = -;code = 45
char = 8;code = 56
char = 1;code = 49
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result sql = Low vitamin D levels have been found in patients with autoimmune diseases, including type I diabetes, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus. The main source of vitamin D is exposure to sunlight, but the same solar radiation is known to exacerbate lupus erythematosus. We investigated the prevalence of vitamin D insufficiency in patients with cutaneous lupus erythematosus (CLE). We designed a cross-sectional study including 55 patients with CLE to measure their serum 25-hydroxyvitamin D (25(OH)D) by chemiluminescence immunoassay and compare it with a control group consisting of 37 healthy sex and age-matched subjects recruited from the patients' relatives as well as healthcare workers. Correlations with clinical and demographic variables were determined. Approximately 95% of patients with CLE had less than 30 ng/ml of serum 25(OH)D, which is accepted as the lower limit for vitamin D adequacy. Mean serum vitamin D values were significantly lower than controls (p = 0.038) and were associated with higher levels of parathyroid hormone (p = 0.050). A history of CLE was a strong predictor of insufficiency of vitamin D (odds ratio 4.2; 95% confidence interval 1.0-17.4). The results suggest a role of CLE in the metabolism of the vitamin and provide guidance for future studies looking at a potential role for vitamin D in the prevention and treatment of CLE. Lupus (2010) 19, 810-814.

Publication: Lupus 2010 Jun ;19(7)::810-4. :doi: 10.1177/0961203309360807.
Publication Date: 2010 Jun
Study Author(s): Cutillas-Marco, E;Morales-Suárez-Varela, Mm;Marquina-Vila, A;Grant, Wb;
Institution: Department of Dermatology, University Hospital Dr Peset, Valencia, Spain.
Shortcut link to this study:
Low vitamin D levels have been found in patients with autoimmune diseases, including type I diabetes, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus. The main source of vitamin D is exposure to sunlight, but the same solar radiation is known to exacerbate lupus erythematosus. We investigated the prevalence of vitamin D insufficiency in patients with cutaneous lupus erythematosus (CLE). We designed a cross-sectional study including 55 patients with CLE to measure their serum 25-hydroxyvitamin D (25(OH)D) by chemiluminescence immunoassay and compare it with a control group consisting of 37 healthy sex and age-matched subjects recruited from the patients' relatives as well as healthcare workers. Correlations with clinical and demographic variables were determined. Approximately 95% of patients with CLE had less than 30 ng/ml of serum 25(OH)D, which is accepted as the lower limit for vitamin D adequacy. Mean serum vitamin D values were significantly lower than controls (p = 0.038) and were associated with higher levels of parathyroid hormone (p = 0.050). A history of CLE was a strong predictor of insufficiency of vitamin D (odds ratio 4.2; 95% confidence interval 1.0-17.4). The results suggest a role of CLE in the metabolism of the vitamin and provide guidance for future studies looking at a potential role for vitamin D in the prevention and treatment of CLE. Lupus (2010) 19, 810-814.
PMID: 20305048

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