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char = ;code = 32
char = f;code = 102
char = i;code = 105
char = b;code = 98
char = e;code = 101
char = r;code = 114
char = s;code = 115
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char = r;code = 114
char = e;code = 101
char = d;code = 100
char = u;code = 117
char = c;code = 99
char = e;code = 101
char = ;code = 32
char = f;code = 102
char = a;code = 97
char = s;code = 115
char = t;code = 116
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = g;code = 103
char = l;code = 108
char = u;code = 117
char = c;code = 99
char = o;code = 111
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = u;code = 117
char = r;code = 114
char = n;code = 110
char = o;code = 111
char = v;code = 118
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = b;code = 98
char = u;code = 117
char = t;code = 116
char = ;code = 32
char = n;code = 110
char = o;code = 111
char = t;code = 116
char = ;code = 32
char = p;code = 112
char = e;code = 101
char = r;code = 114
char = i;code = 105
char = p;code = 112
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = s;code = 115
char = u;code = 117
char = l;code = 108
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = i;code = 105
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = m;code = 109
char = e;code = 101
char = t;code = 116
char = a;code = 97
char = b;code = 98
char = o;code = 111
char = l;code = 108
char = i;code = 105
char = c;code = 99
char = ;code = 32
char = s;code = 115
char = y;code = 121
char = n;code = 110
char = d;code = 100
char = r;code = 114
char = o;code = 111
char = m;code = 109
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = .;code = 46
result sql = Acetogenic fibers reduce fasting glucose turnover but not peripheral insulin resistance in metabolic syndrome patients.
Acetogenic fibers reduce fasting glucose turnover but not peripheral insulin resistance in metabolic syndrome patients.
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = B;code = 66
char = A;code = 65
char = C;code = 67
char = K;code = 75
char = G;code = 71
char = R;code = 82
char = O;code = 79
char = U;code = 85
char = N;code = 78
char = D;code = 68
char = ;code = 32
char = &;code = 38
char = ;code = 32
char = A;code = 65
char = I;code = 73
char = M;code = 77
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
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char = >;code = 62
char = T;code = 84
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char = e;code = 101
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char = a;code = 97
char = c;code = 99
char = u;code = 117
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char = e;code = 101
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char = n;code = 110
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char = o;code = 111
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char = o;code = 111
char = f;code = 102
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char = (;code = 40
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char = a;code = 97
char = c;code = 99
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char = u;code = 117
char = l;code = 108
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char = e;code = 101
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char = ;code = 32
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char = d;code = 100
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char = t;code = 116
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char = s;code = 115
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char = d;code = 100
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char = t;code = 116
char = h;code = 104
char = ;code = 32
char = d;code = 100
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char = c;code = 99
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char = e;code = 101
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = d;code = 100
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char = i;code = 105
char = p;code = 112
char = o;code = 111
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char = s;code = 115
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char = (;code = 40
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char = p;code = 112
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char = i;code = 105
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = .;code = 46
char = ;code = 32
char = I;code = 73
char = t;code = 116
char = ;code = 32
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = n;code = 110
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char = t;code = 116
char = ;code = 32
char = k;code = 107
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char = ;code = 32
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char = o;code = 111
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char = ;code = 32
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char = c;code = 99
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char = o;code = 111
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char = a;code = 97
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char = e;code = 101
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char = o;code = 111
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char = f;code = 102
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char = s;code = 115
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char = m;code = 109
char = p;code = 112
char = r;code = 114
char = o;code = 111
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char = e;code = 101
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char = ;code = 32
char = g;code = 103
char = l;code = 108
char = u;code = 117
char = c;code = 99
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char = e;code = 101
char = ;code = 32
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char = o;code = 111
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char = <;code = 60
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char = r;code = 114
char = /;code = 47
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char = <;code = 60
char = b;code = 98
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char = M;code = 77
char = E;code = 69
char = T;code = 84
char = H;code = 72
char = O;code = 79
char = D;code = 68
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
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char = >;code = 62
char = T;code = 84
char = w;code = 119
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char = t;code = 116
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char = a;code = 97
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char = s;code = 115
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char = d;code = 100
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char = u;code = 117
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char = 2;code = 50
char = 8;code = 56
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char = g;code = 103
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char = (;code = 40
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char = a;code = 97
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char = <;code = 60
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char = R;code = 82
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char = S;code = 83
char = U;code = 85
char = L;code = 76
char = T;code = 84
char = S;code = 83
char = ;code = 32
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char = ;code = 32
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char = m;code = 109
char = o;code = 111
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char = y;code = 121
char = n;code = 110
char = d;code = 100
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char = o;code = 111
char = m;code = 109
char = e;code = 101
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result sql = BACKGROUND & AIMS : The acute ingestion of an acetogenic indigestible carbohydrate (lactulose) increased acetate turnover associated with decreased lipolysis (glycerol turnover) in insulin-resistant patients. It is not known whether a decreased lipolysis by chronic ingestion of acetogenic indigestible carbohydrates or fibers improves glucose turnover and insulin sensitivity.

METHODS : Twenty-one men with metabolic syndrome ingested daily standardized drinks, with or without 28 g acetogenic fibers (acacia gum and pectin), for 5 weeks in a randomized double-blind crossover controlled study design. Euglycaemic-hyperinsulinaemic (EH) clamps coupled with kinetic studies were performed in the fasting state after treatments.

RESULTS : Flatulence was more frequent with fiber treatment. Body weight, lipids as well as acetate and glycerol turnovers were unchanged. Fasting endogenous glucose turnover was improved after fiber treatment (7.9 ± 1.3 μmol kg(-1) min(-1)) compared with control (8.6 ± 1.6 μmol kg(-1) min(-1), P < 0.05). But insulin sensitivity (glucose infusion rate) during the EH clamp was not different at the end of fiber and control treatments, 3.7 ± 1.8 and 3.8 ± 1.5 mg kg(-1) min(-1), respectively, nor fasting plasma glucose and insulin.

CONCLUSIONS : The chronic ingestion of acacia gum and pectin fibers did not decrease lipolysis but improved fasting endogenous glucose turnover with no effect on peripheral insulin resistance in metabolic syndrome patients.

Publication: Clin Nutr 2010 Dec ;29(6)::801-7. :doi: 10.1016/j.clnu.2010.05.006.
Publication Date: 2010 Dec
Study Author(s): Pouteau, Etienne;Ferchaud-Roucher, Véronique;Zair, Yassine;Paintin, Morine;Enslen, Marc;Auriou, Nicolas;Macé, Katherine;Godin, Jean-Philippe;Ballèvre, Olivier;Krempf, Michel;
Institution: Nestlé Research Centre, P.O. Box 44, Vers-Chez-Les-Blanc, 1000 Lausanne 26, Switzerland. [email protected]
Shortcut link to this study:
BACKGROUND & AIMS : The acute ingestion of an acetogenic indigestible carbohydrate (lactulose) increased acetate turnover associated with decreased lipolysis (glycerol turnover) in insulin-resistant patients. It is not known whether a decreased lipolysis by chronic ingestion of acetogenic indigestible carbohydrates or fibers improves glucose turnover and insulin sensitivity.

METHODS : Twenty-one men with metabolic syndrome ingested daily standardized drinks, with or without 28 g acetogenic fibers (acacia gum and pectin), for 5 weeks in a randomized double-blind crossover controlled study design. Euglycaemic-hyperinsulinaemic (EH) clamps coupled with kinetic studies were performed in the fasting state after treatments.

RESULTS : Flatulence was more frequent with fiber treatment. Body weight, lipids as well as acetate and glycerol turnovers were unchanged. Fasting endogenous glucose turnover was improved after fiber treatment (7.9 ± 1.3 μmol kg(-1) min(-1)) compared with control (8.6 ± 1.6 μmol kg(-1) min(-1), P < 0.05). But insulin sensitivity (glucose infusion rate) during the EH clamp was not different at the end of fiber and control treatments, 3.7 ± 1.8 and 3.8 ± 1.5 mg kg(-1) min(-1), respectively, nor fasting plasma glucose and insulin.

CONCLUSIONS : The chronic ingestion of acacia gum and pectin fibers did not decrease lipolysis but improved fasting endogenous glucose turnover with no effect on peripheral insulin resistance in metabolic syndrome patients.
PMID: 20584565

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