char = I;code = 73
International reproducibility of single breathhold T2* MR for cardiac and liver iron assessment among five thalassemia centers.char = <;code = 60PURPOSE : To examine the reproducibility of the single breathhold T2* technique from different scanners, after installation of standard methodology in five international centers.MATERIALS AND METHODS : Up to 10 patients from each center were scanned twice locally for local interstudy reproducibility of heart and liver T2*, and then flown to a central MR facility to be rescanned on a reference scanner for intercenter reproducibility. Interobserver reproducibility for all scans was also assessed.RESULTS : Of the 49 patients scanned, the intercenter reproducibility for T2* was 5.9% for the heart and 5.8% for the liver. Local interstudy reproducibility for T2* was 7.4% for the heart and 4.6% for the liver. Interobserver reproducibility for T2* was 5.4% for the heart and 4.4% for the liver.CONCLUSION : These data indicate that T2* MR may be developed into a widespread test for tissue siderosis providing that well-defined and approved imaging and analysis techniques are used.
Publication: J Magn Reson Imaging 2010 Aug ;32(2)::315-9. :doi: 10.1002/jmri.22245.
PURPOSE : To examine the reproducibility of the single breathhold T2* technique from different scanners, after installation of standard methodology in five international centers.MATERIALS AND METHODS : Up to 10 patients from each center were scanned twice locally for local interstudy reproducibility of heart and liver T2*, and then flown to a central MR facility to be rescanned on a reference scanner for intercenter reproducibility. Interobserver reproducibility for all scans was also assessed.RESULTS : Of the 49 patients scanned, the intercenter reproducibility for T2* was 5.9% for the heart and 5.8% for the liver. Local interstudy reproducibility for T2* was 7.4% for the heart and 4.6% for the liver. Interobserver reproducibility for T2* was 5.4% for the heart and 4.4% for the liver.CONCLUSION : These data indicate that T2* MR may be developed into a widespread test for tissue siderosis providing that well-defined and approved imaging and analysis techniques are used.
PMID: 20677256
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