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char = g;code = 103
char = n;code = 110
char = e;code = 101
char = t;code = 116
char = i;code = 105
char = c;code = 99
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char = s;code = 115
char = o;code = 111
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char = n;code = 110
char = c;code = 99
char = e;code = 101
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char = p;code = 112
char = e;code = 101
char = c;code = 99
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char = r;code = 114
char = o;code = 111
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char = c;code = 99
char = o;code = 111
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char = y;code = 121
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char = R;code = 82
char = S;code = 83
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char = m;code = 109
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char = g;code = 103
char = r;code = 114
char = a;code = 97
char = i;code = 105
char = n;code = 110
char = e;code = 101
char = ];code = 93
char = .;code = 46
result sql = [Magnetic resonance spectroscopy (HMRS) in migraine].
[Magnetic resonance spectroscopy (HMRS) in migraine].
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = I;code = 73
char = N;code = 78
char = T;code = 84
char = R;code = 82
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char = D;code = 68
char = U;code = 85
char = C;code = 67
char = T;code = 84
char = I;code = 73
char = O;code = 79
char = N;code = 78
char = ;code = 32
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char = ;code = 32
char = <;code = 60
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char = h;code = 104
char = e;code = 101
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char = ;code = 32
char = a;code = 97
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = 4;code = 52
char = ;code = 32
char = m;code = 109
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char = l;code = 108
char = l;code = 108
char = i;code = 105
char = o;code = 111
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char = o;code = 111
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char = l;code = 108
char = e;code = 101
char = ;code = 32
char = s;code = 115
char = u;code = 117
char = f;code = 102
char = f;code = 102
char = e;code = 101
char = r;code = 114
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char = n;code = 110
char = g;code = 103
char = ;code = 32
char = f;code = 102
char = r;code = 114
char = o;code = 111
char = m;code = 109
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char = m;code = 109
char = i;code = 105
char = g;code = 103
char = r;code = 114
char = a;code = 97
char = i;code = 105
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = P;code = 80
char = o;code = 111
char = l;code = 108
char = a;code = 97
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char = d;code = 100
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char = i;code = 105
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char = ;code = 32
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char = c;code = 99
char = c;code = 99
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char = n;code = 110
char = t;code = 116
char = ;;code = 59
char = ;code = 32
char = f;code = 102
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char = r;code = 114
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char = 1;code = 49
char = 0;code = 48
char = %;code = 37
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = n;code = 110
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = p;code = 112
char = o;code = 111
char = p;code = 112
char = u;code = 117
char = l;code = 108
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = .;code = 46
char = ;code = 32
char = P;code = 80
char = a;code = 97
char = t;code = 116
char = h;code = 104
char = o;code = 111
char = m;code = 109
char = e;code = 101
char = c;code = 99
char = h;code = 104
char = a;code = 97
char = n;code = 110
char = i;code = 105
char = s;code = 115
char = m;code = 109
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = m;code = 109
char = i;code = 105
char = g;code = 103
char = r;code = 114
char = a;code = 97
char = i;code = 105
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = n;code = 110
char = o;code = 111
char = t;code = 116
char = ;code = 32
char = f;code = 102
char = u;code = 117
char = l;code = 108
char = l;code = 108
char = y;code = 121
char = ;code = 32
char = u;code = 117
char = n;code = 110
char = d;code = 100
char = e;code = 101
char = r;code = 114
char = s;code = 115
char = t;code = 116
char = o;code = 111
char = o;code = 111
char = d;code = 100
char = .;code = 46
char = ;code = 32
char = I;code = 73
char = n;code = 110
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = c;code = 99
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = y;code = 121
char = e;code = 101
char = a;code = 97
char = r;code = 114
char = s;code = 115
char = ;code = 32
char = m;code = 109
char = u;code = 117
char = l;code = 108
char = t;code = 116
char = i;code = 105
char = p;code = 112
char = l;code = 108
char = e;code = 101
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = u;code = 117
char = d;code = 100
char = i;code = 105
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = m;code = 109
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char = g;code = 103
char = r;code = 114
char = a;code = 97
char = i;code = 105
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char = p;code = 112
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = e;code = 101
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char = t;code = 116
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char = r;code = 114
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char = e;code = 101
char = a;code = 97
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char = e;code = 101
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char = r;code = 114
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char = c;code = 99
char = e;code = 101
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char = o;code = 111
char = f;code = 102
char = ;code = 32
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char = t;code = 116
char = a;code = 97
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char = i;code = 105
char = c;code = 99
char = ;code = 32
char = d;code = 100
char = i;code = 105
char = s;code = 115
char = o;code = 111
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char = d;code = 100
char = e;code = 101
char = r;code = 114
char = s;code = 115
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char = i;code = 105
char = n;code = 110
char = ;code = 32
char = n;code = 110
char = e;code = 101
char = r;code = 114
char = v;code = 118
char = o;code = 111
char = u;code = 117
char = s;code = 115
char = ;code = 32
char = s;code = 115
char = y;code = 121
char = s;code = 115
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char = e;code = 101
char = m;code = 109
char = ;code = 32
char = t;code = 116
char = i;code = 105
char = s;code = 115
char = s;code = 115
char = u;code = 117
char = e;code = 101
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = M;code = 77
char = A;code = 65
char = T;code = 84
char = E;code = 69
char = R;code = 82
char = I;code = 73
char = A;code = 65
char = L;code = 76
char = ;code = 32
char = A;code = 65
char = N;code = 78
char = D;code = 68
char = ;code = 32
char = M;code = 77
char = E;code = 69
char = T;code = 84
char = H;code = 72
char = O;code = 79
char = D;code = 68
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = I;code = 73
char = n;code = 110
char = ;code = 32
char = 3;code = 51
char = 0;code = 48
char = ;code = 32
char = s;code = 115
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char = b;code = 98
char = j;code = 106
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = m;code = 109
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char = g;code = 103
char = r;code = 114
char = a;code = 97
char = i;code = 105
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = d;code = 100
char = i;code = 105
char = a;code = 97
char = g;code = 103
char = n;code = 110
char = o;code = 111
char = s;code = 115
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = m;code = 109
char = a;code = 97
char = g;code = 103
char = n;code = 110
char = e;code = 101
char = t;code = 116
char = i;code = 105
char = c;code = 99
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = o;code = 111
char = n;code = 110
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = ;code = 32
char = s;code = 115
char = p;code = 112
char = e;code = 101
char = c;code = 99
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char = r;code = 114
char = o;code = 111
char = s;code = 115
char = c;code = 99
char = o;code = 111
char = p;code = 112
char = y;code = 121
char = ;code = 32
char = e;code = 101
char = x;code = 120
char = a;code = 97
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
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char = a;code = 97
char = s;code = 115
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char = e;code = 101
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char = f;code = 102
char = o;code = 111
char = r;code = 114
char = m;code = 109
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char = d;code = 100
char = .;code = 46
char = ;code = 32
char = R;code = 82
char = e;code = 101
char = l;code = 108
char = a;code = 97
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char = v;code = 118
char = e;code = 101
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char = c;code = 99
char = o;code = 111
char = n;code = 110
char = c;code = 99
char = e;code = 101
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char = r;code = 114
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char = t;code = 116
char = i;code = 105
char = o;code = 111
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char = o;code = 111
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char = S;code = 83
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char = m;code = 109
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char = e;code = 101
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char = e;code = 101
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char = g;code = 103
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char = l;code = 108
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char = t;code = 116
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char = m;code = 109
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char = a;code = 97
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char = ;code = 32
char = l;code = 108
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char = a;code = 97
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char = S;code = 83
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char = r;code = 114
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char = v;code = 118
char = a;code = 97
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char = a;code = 97
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char = S;code = 83
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char = n;code = 110
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char = o;code = 111
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char = ;code = 32
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char = u;code = 117
char = b;code = 98
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char = s;code = 115
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char = d;code = 100
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = n;code = 110
char = t;code = 116
char = r;code = 114
char = o;code = 111
char = l;code = 108
char = ;code = 32
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result sql = INTRODUCTION : There are 4 million people suffering from migraine in Poland, which account; for 10% of national population. Pathomechanism of migraine is not fully understood. In the recent years multiple studies in migraine patients revealed occurrence of metabolic disorders in nervous system tissue.

MATERIAL AND METHODS : In 30 subjects with migraine diagnosis magnetic resonance spectroscopy examination was performed. Relative concentration ratio (WSS) of metabolites level to creatinine (Cr) level was measured. The obtained values were compared to findings in control groups.

RESULTS : Linear correlation between increase in both WSS Lac/Cr value in left temporal lobe and WSS ml/Cr value in right frontal lobe and a number of migraine attacks per year in migraine patients was observed. It also turned out that WSS ml/Cr vox3 value depends on a total number of migraine attacks in life. A lactic acid level in left temporal lobe normalizes along with the elongation of interattack interval. There is a statistically significant difference of WSS ml/Cr value measured in left temporal lobe and right frontal lobe between migraine patients and control group. There is a statistically significant difference of WSS Cho/Cr value measured in left temporal lobe and right frontal lobe between migraine subjects and control groups.

Publication: Prz. Lek. 2010 ;67(4)::251-5.
Publication Date: 2010
Study Author(s): Trabka-Janik, Elzbieta;Kułaga, Agnieszka;Urbanik, Andrzej;Szczudlik, Andrzej;Grzybek, Magdalena;
Institution: Katedra i Klinika Neurologii, Uniwersytet Jagielloński Collegium Medicum.
Shortcut link to this study:
INTRODUCTION : There are 4 million people suffering from migraine in Poland, which account; for 10% of national population. Pathomechanism of migraine is not fully understood. In the recent years multiple studies in migraine patients revealed occurrence of metabolic disorders in nervous system tissue.

MATERIAL AND METHODS : In 30 subjects with migraine diagnosis magnetic resonance spectroscopy examination was performed. Relative concentration ratio (WSS) of metabolites level to creatinine (Cr) level was measured. The obtained values were compared to findings in control groups.

RESULTS : Linear correlation between increase in both WSS Lac/Cr value in left temporal lobe and WSS ml/Cr value in right frontal lobe and a number of migraine attacks per year in migraine patients was observed. It also turned out that WSS ml/Cr vox3 value depends on a total number of migraine attacks in life. A lactic acid level in left temporal lobe normalizes along with the elongation of interattack interval. There is a statistically significant difference of WSS ml/Cr value measured in left temporal lobe and right frontal lobe between migraine patients and control group. There is a statistically significant difference of WSS Cho/Cr value measured in left temporal lobe and right frontal lobe between migraine subjects and control groups.
PMID: 20687355

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