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result sql = Acute calcium ingestion attenuates exercise-induced disruption of calcium homeostasis.

Acute calcium ingestion attenuates exercise-induced disruption of calcium homeostasis.

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char = ;code = 32
char = a;code = 97
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char = d;code = 100
char = ;code = 32
char = d;code = 100
char = u;code = 117
char = r;code = 114
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char = n;code = 110
char = g;code = 103
char = ;code = 32
char = e;code = 101
char = x;code = 120
char = e;code = 101
char = r;code = 114
char = c;code = 99
char = i;code = 105
char = s;code = 115
char = e;code = 101
char = .;code = 46
char = ;code = 32
char = C;code = 67
char = a;code = 97
char = l;code = 108
char = c;code = 99
char = i;code = 105
char = u;code = 117
char = m;code = 109
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char = w;code = 119
char = a;code = 97
char = s;code = 115
char = ;code = 32
char = d;code = 100
char = e;code = 101
char = l;code = 108
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = r;code = 114
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = 1;code = 49
char = 0;code = 48
char = 0;code = 48
char = 0;code = 48
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char = m;code = 109
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char = #;code = 35
char = 1;code = 49
char = 8;code = 56
char = 3;code = 51
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char = 1;code = 49
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char = ;code = 32
char = s;code = 115
char = o;code = 111
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char = u;code = 117
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = .;code = 46
char = ;code = 32
char = S;code = 83
char = u;code = 117
char = p;code = 112
char = p;code = 112
char = l;code = 108
char = e;code = 101
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
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char = w;code = 119
char = a;code = 97
char = s;code = 115
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char = d;code = 100
char = o;code = 111
char = u;code = 117
char = b;code = 98
char = l;code = 108
char = e;code = 101
char = -;code = 45
char = b;code = 98
char = l;code = 108
char = i;code = 105
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char = e;code = 101
char = d;code = 100
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char = ;code = 32
char = a;code = 97
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char = d;code = 100
char = ;code = 32
char = t;code = 116
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char = i;code = 105
char = a;code = 97
char = l;code = 108
char = s;code = 115
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char = w;code = 119
char = e;code = 101
char = r;code = 114
char = e;code = 101
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char = p;code = 112
char = e;code = 101
char = r;code = 114
char = f;code = 102
char = o;code = 111
char = r;code = 114
char = m;code = 109
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = i;code = 105
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char = ;code = 32
char = r;code = 114
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = o;code = 111
char = m;code = 109
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char = o;code = 111
char = r;code = 114
char = d;code = 100
char = e;code = 101
char = r;code = 114
char = .;code = 46
char = ;code = 32
char = P;code = 80
char = T;code = 84
char = H;code = 72
char = ,;code = 44
char = ;code = 32
char = C;code = 67
char = T;code = 84
char = X;code = 88
char = ,;code = 44
char = ;code = 32
char = b;code = 98
char = o;code = 111
char = n;code = 110
char = e;code = 101
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char = s;code = 115
char = p;code = 112
char = e;code = 101
char = c;code = 99
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
char = ;code = 32
char = a;code = 97
char = l;code = 108
char = k;code = 107
char = a;code = 97
char = l;code = 108
char = i;code = 105
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = h;code = 104
char = o;code = 111
char = s;code = 115
char = p;code = 112
char = h;code = 104
char = a;code = 97
char = t;code = 116
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = B;code = 66
char = A;code = 65
char = P;code = 80
char = ;;code = 59
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = m;code = 109
char = a;code = 97
char = r;code = 114
char = k;code = 107
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = b;code = 98
char = o;code = 111
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = f;code = 102
char = o;code = 111
char = r;code = 114
char = m;code = 109
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
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char = ,;code = 44
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = i;code = 105
char = o;code = 111
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char = i;code = 105
char = z;code = 122
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = l;code = 108
char = c;code = 99
char = i;code = 105
char = u;code = 117
char = m;code = 109
char = ;code = 32
char = (;code = 40
char = i;code = 105
char = C;code = 67
char = a;code = 97
char = );code = 41
char = ;code = 32
char = w;code = 119
char = e;code = 101
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = m;code = 109
char = e;code = 101
char = a;code = 97
char = s;code = 115
char = u;code = 117
char = r;code = 114
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = b;code = 98
char = e;code = 101
char = f;code = 102
char = o;code = 111
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = a;code = 97
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char = d;code = 100
char = ;code = 32
char = i;code = 105
char = m;code = 109
char = m;code = 109
char = e;code = 101
char = d;code = 100
char = i;code = 105
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = l;code = 108
char = y;code = 121
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char = a;code = 97
char = f;code = 102
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = e;code = 101
char = x;code = 120
char = e;code = 101
char = r;code = 114
char = c;code = 99
char = i;code = 105
char = s;code = 115
char = e;code = 101
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = R;code = 82
char = E;code = 69
char = S;code = 83
char = U;code = 85
char = L;code = 76
char = T;code = 84
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = C;code = 67
char = T;code = 84
char = X;code = 88
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = c;code = 99
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = a;code = 97
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char = d;code = 100
char = ;code = 32
char = i;code = 105
char = C;code = 67
char = a;code = 97
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char = d;code = 100
char = e;code = 101
char = c;code = 99
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = m;code = 109
char = i;code = 105
char = l;code = 108
char = a;code = 97
char = r;code = 114
char = l;code = 108
char = y;code = 121
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char = i;code = 105
char = n;code = 110
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char = r;code = 114
char = e;code = 101
char = s;code = 115
char = p;code = 112
char = o;code = 111
char = n;code = 110
char = s;code = 115
char = e;code = 101
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char = e;code = 101
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char = e;code = 101
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char = c;code = 99
char = i;code = 105
char = s;code = 115
char = e;code = 101
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char = u;code = 117
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char = d;code = 100
char = e;code = 101
char = r;code = 114
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char = a;code = 97
char = l;code = 108
char = l;code = 108
char = ;code = 32
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char = e;code = 101
char = s;code = 115
char = t;code = 116
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char = c;code = 99
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char = i;code = 105
char = o;code = 111
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char = s;code = 115
char = .;code = 46
char = ;code = 32
char = W;code = 87
char = h;code = 104
char = e;code = 101
char = n;code = 110
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char = c;code = 99
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char = m;code = 109
char = p;code = 112
char = a;code = 97
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char = e;code = 101
char = d;code = 100
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char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = p;code = 112
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char = a;code = 97
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char = e;code = 101
char = b;code = 98
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char = ,;code = 44
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char = c;code = 99
char = a;code = 97
char = l;code = 108
char = c;code = 99
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char = u;code = 117
char = m;code = 109
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char = s;code = 115
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char = p;code = 112
char = l;code = 108
char = e;code = 101
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char = e;code = 101
char = n;code = 110
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char = a;code = 97
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char = i;code = 105
char = o;code = 111
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char = ;code = 32
char = b;code = 98
char = e;code = 101
char = f;code = 102
char = o;code = 111
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char = e;code = 101
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char = e;code = 101
char = x;code = 120
char = e;code = 101
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char = c;code = 99
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char = s;code = 115
char = e;code = 101
char = ;code = 32
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char = t;code = 116
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char = u;code = 117
char = a;code = 97
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char = e;code = 101
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char = t;code = 116
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char = i;code = 105
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char = c;code = 99
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char = e;code = 101
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = P;code = 80
char = T;code = 84
char = H;code = 72
char = ;code = 32
char = (;code = 40
char = m;code = 109
char = e;code = 101
char = a;code = 97
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char = &;code = 38
char = #;code = 35
char = 1;code = 49
char = 7;code = 55
char = 7;code = 55
char = ;;code = 59
char = ;code = 32
char = S;code = 83
char = E;code = 69
char = :;code = 58
char = ;code = 32
char = 5;code = 53
char = 5;code = 53
char = .;code = 46
char = 8;code = 56
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char = &;code = 38
char = #;code = 35
char = 1;code = 49
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char = 7;code = 55
char = ;;code = 59
char = ;code = 32
char = 1;code = 49
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char = .;code = 46
char = 0;code = 48
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char = v;code = 118
char = s;code = 115
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char = 7;code = 55
char = 4;code = 52
char = .;code = 46
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char = ;code = 32
char = &;code = 38
char = #;code = 35
char = 1;code = 49
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char = 7;code = 55
char = ;;code = 59
char = ;code = 32
char = 1;code = 49
char = 4;code = 52
char = .;code = 46
char = 2;code = 50
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char = p;code = 112
char = g;code = 103
char = &;code = 38
char = #;code = 35
char = 1;code = 49
char = 8;code = 56
char = 3;code = 51
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char = m;code = 109
char = L;code = 76
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char = -;code = 45
char = 1;code = 49
char = );code = 41
char = ,;code = 44
char = ;code = 32
char = P;code = 80
char = ;code = 32
char = =;code = 61
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char = 0;code = 48
char = .;code = 46
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char = 4;code = 52
char = );code = 41
char = ;;code = 59
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = r;code = 114
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char = ;code = 32
char = w;code = 119
char = a;code = 97
char = s;code = 115
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = s;code = 115
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char = m;code = 109
char = i;code = 105
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char = a;code = 97
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char = t;code = 116
char = r;code = 114
char = e;code = 101
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char = d;code = 100
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char = (;code = 40
char = 5;code = 53
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char = .;code = 46
char = 0;code = 48
char = ;code = 32
char = &;code = 38
char = #;code = 35
char = 1;code = 49
char = 7;code = 55
char = 7;code = 55
char = ;;code = 59
char = ;code = 32
char = 1;code = 49
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char = .;code = 46
char = 4;code = 52
char = ,;code = 44
char = ;code = 32
char = P;code = 80
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char = =;code = 61
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char = 0;code = 48
char = .;code = 46
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char = 7;code = 55
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char = ;code = 32
char = f;code = 102
char = o;code = 111
char = r;code = 114
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char = c;code = 99
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char = u;code = 117
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char = i;code = 105
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char = T;code = 84
char = h;code = 104
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char = e;code = 101
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char = e;code = 101
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char = a;code = 97
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char = e;code = 101
char = s;code = 115
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char = C;code = 67
char = T;code = 84
char = X;code = 88
char = ,;code = 44
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char = B;code = 66
char = A;code = 65
char = P;code = 80
char = ,;code = 44
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char = a;code = 97
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char = i;code = 105
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char = a;code = 97
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char = <;code = 60
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char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = C;code = 67
char = O;code = 79
char = N;code = 78
char = C;code = 67
char = L;code = 76
char = U;code = 85
char = S;code = 83
char = I;code = 73
char = O;code = 79
char = N;code = 78
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
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char = >;code = 62
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char = i;code = 105
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char = f;code = 102
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char = s;code = 115
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char = t;code = 116
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char = a;code = 97
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char = o;code = 111
char = n;code = 110
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = P;code = 80
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char = H;code = 72
char = .;code = 46
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char = F;code = 70
char = u;code = 117
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char = t;code = 116
char = h;code = 104
char = e;code = 101
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char = a;code = 97
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char = e;code = 101
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char = t;code = 116
char = e;code = 101
char = r;code = 114
char = m;code = 109
char = i;code = 105
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result sql = PURPOSE : Exercise is associated with a decrease in bone mineral density under certain conditions. One potential mechanism is increased bone resorption due to an exercise-induced increase in parathyroid hormone (PTH), possibly triggered by dermal calcium loss. The purpose of this investigation was to determine whether calcium supplementation either before or during exercise attenuates exercise-induced increases in PTH and C-terminal telopeptide of Type I collagen (CTX; a marker of bone resorption).

METHODS : Male endurance athletes (n = 20) completed three 35-km cycling time trials under differing calcium supplementation conditions: 1) 1000 mg of calcium 20 min before exercise and placebo during, 2) placebo before and 250 mg of calcium every 15 min during exercise (1000 mg total), or 3) placebo before and during exercise. Calcium was delivered in a 1000-mg·L(-1) solution. Supplementation was double-blinded, and trials were performed in random order. PTH, CTX, bone-specific alkaline phosphatase (BAP; a marker of bone formation), and ionized calcium (iCa) were measured before and immediately after exercise.

RESULTS : CTX increased and iCa decreased similarly in response to exercise under all test conditions. When compared with placebo, calcium supplementation before exercise attenuated the increase in PTH (mean ± SE: 55.8 ± 15.0 vs 74.0 ± 14.2 pg·mL(-1), P = 0.04); there was a similar trend (58.0 ± 17.4, P = 0.07) for calcium supplementation during exercise. There were no effects of calcium on changes in CTX, BAP, and iCa.

CONCLUSIONS : Calcium supplementation before exercise attenuated the disruption of PTH. Further research is needed to determine the effects of repeated increases in PTH and CTX on bone (i.e., exercise training) and whether calcium supplementation can diminish any exercise-induced demineralization.

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