|
|
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result sql = A successfully treated case of herpes simplex encephalitis complicated by subarachnoid bleeding: a case report.
A successfully treated case of herpes simplex encephalitis complicated by subarachnoid bleeding: a case report.char = <;code = 60
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result sql = INTRODUCTION : Histopathologically, herpes simplex virus type 1 causes hemorrhagic necrosis. Overt hemorrhage is infrequent in herpes simplex virus encephalitis but can lead to poor outcomes. This report describes a successfully treated case of herpes simplex virus encephalitis associated with subarachnoid bleeding in which real-time polymerase chain reaction was useful for diagnosis.
CASE PRESENTATION : A 30-year-old previously healthy Japanese woman who had fever and headache for five days presented with disorganised speech, unusual behavior and delusional thinking. Real-time polymerase chain reaction amplification of herpes simplex virus type 1 in cerebrospinal fluid was positive (38,000 copies/mL) and antivirus treatment was started. During the course of her illness, the level of her consciousness decreased in association with desaturation and tachycardia. Thrombosis of the right pulmonary artery trunk with pulmonary embolism was evident on enhanced chest computed tomography. In addition, cranial computed tomography revealed subarachnoid and intraventricular bleeding. Intravenous heparin (12,000 U/day) was started and the dose was adjusted according to the activated partial thromboplastin time for about a month (maximum dose of heparin, 20,400 U/day). After the treatments, her Glasgow coma score increased and the thrombosis of the pulmonary artery trunk had disappeared.
CONCLUSIONS : The present case raises the question of whether anticoagulant treatment is safe in patients with herpes simplex virus encephalitis complicated by subarachnoid bleeding.
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char = r;code = 114
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result sql = A successfully treated case of herpes simplex encephalitis complicated by subarachnoid bleeding: a case report.
char = b;code = 98
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char = C;code = 67
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char = s;code = 115
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char = r;code = 114
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char = e;code = 101
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char = s;code = 115
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char = m;code = 109
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char = v;code = 118
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char = i;code = 105
char = s;code = 115
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char = b;code = 98
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char = m;code = 109
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char = .;code = 46
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char = i;code = 105
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char = s;code = 115
char = o;code = 111
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char = b;code = 98
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char = a;code = 97
char = c;code = 99
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char = b;code = 98
char = l;code = 108
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char = e;code = 101
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char = g;code = 103
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char = i;code = 105
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char = h;code = 104
char = i;code = 105
char = c;code = 99
char = h;code = 104
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char = a;code = 97
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char = s;code = 115
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char = u;code = 117
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char = .;code = 46
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char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = C;code = 67
char = A;code = 65
char = S;code = 83
char = E;code = 69
char = ;code = 32
char = P;code = 80
char = R;code = 82
char = E;code = 69
char = S;code = 83
char = E;code = 69
char = N;code = 78
char = T;code = 84
char = A;code = 65
char = T;code = 84
char = I;code = 73
char = O;code = 79
char = N;code = 78
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = A;code = 65
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char = 3;code = 51
char = 0;code = 48
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char = a;code = 97
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char = -;code = 45
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char = d;code = 100
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char = v;code = 118
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char = h;code = 104
char = e;code = 101
char = a;code = 97
char = l;code = 108
char = t;code = 116
char = h;code = 104
char = y;code = 121
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char = J;code = 74
char = a;code = 97
char = p;code = 112
char = a;code = 97
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char = k;code = 107
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char = e;code = 101
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char = t;code = 116
char = i;code = 105
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char = e;code = 101
char = n;code = 110
char = o;code = 111
char = u;code = 117
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char = h;code = 104
char = e;code = 101
char = p;code = 112
char = a;code = 97
char = r;code = 114
char = i;code = 105
char = n;code = 110
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char = 0;code = 48
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char = ;code = 32
char = d;code = 100
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char = ;code = 32
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char = ;code = 32
char = a;code = 97
char = d;code = 100
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char = u;code = 117
char = s;code = 115
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char = ;code = 32
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char = c;code = 99
char = c;code = 99
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char = r;code = 114
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char = ;code = 32
char = t;code = 116
char = h;code = 104
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char = ;code = 32
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char = t;code = 116
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char = b;code = 98
char = o;code = 111
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char = ;code = 32
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char = ;code = 32
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char = o;code = 111
char = n;code = 110
char = t;code = 116
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char = (;code = 40
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char = a;code = 97
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char = m;code = 109
char = u;code = 117
char = m;code = 109
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char = f;code = 102
char = ;code = 32
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char = 4;code = 52
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char = d;code = 100
char = a;code = 97
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char = );code = 41
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char = f;code = 102
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = t;code = 116
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = ,;code = 44
char = ;code = 32
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = G;code = 71
char = l;code = 108
char = a;code = 97
char = s;code = 115
char = g;code = 103
char = o;code = 111
char = w;code = 119
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = m;code = 109
char = a;code = 97
char = ;code = 32
char = s;code = 115
char = c;code = 99
char = o;code = 111
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = c;code = 99
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
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char = h;code = 104
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = r;code = 114
char = o;code = 111
char = m;code = 109
char = b;code = 98
char = o;code = 111
char = s;code = 115
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = u;code = 117
char = l;code = 108
char = m;code = 109
char = o;code = 111
char = n;code = 110
char = a;code = 97
char = r;code = 114
char = y;code = 121
char = ;code = 32
char = a;code = 97
char = r;code = 114
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = y;code = 121
char = ;code = 32
char = t;code = 116
char = r;code = 114
char = u;code = 117
char = n;code = 110
char = k;code = 107
char = ;code = 32
char = h;code = 104
char = a;code = 97
char = d;code = 100
char = ;code = 32
char = d;code = 100
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char = p;code = 112
char = e;code = 101
char = a;code = 97
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char = e;code = 101
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char = b;code = 98
char = r;code = 114
char = /;code = 47
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char = b;code = 98
char = r;code = 114
char = /;code = 47
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char = <;code = 60
char = b;code = 98
char = >;code = 62
char = C;code = 67
char = O;code = 79
char = N;code = 78
char = C;code = 67
char = L;code = 76
char = U;code = 85
char = S;code = 83
char = I;code = 73
char = O;code = 79
char = N;code = 78
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
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char = b;code = 98
char = >;code = 62
char = T;code = 84
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char = e;code = 101
char = ;code = 32
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char = r;code = 114
char = e;code = 101
char = s;code = 115
char = e;code = 101
char = n;code = 110
char = t;code = 116
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char = a;code = 97
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char = s;code = 115
char = e;code = 101
char = s;code = 115
char = ;code = 32
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char = u;code = 117
char = l;code = 108
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = t;code = 116
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = t;code = 116
char = m;code = 109
char = e;code = 101
char = n;code = 110
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char = ;code = 32
char = i;code = 105
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char = ;code = 32
char = s;code = 115
char = a;code = 97
char = f;code = 102
char = e;code = 101
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = p;code = 112
char = a;code = 97
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char = i;code = 105
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = p;code = 112
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = m;code = 109
char = p;code = 112
char = l;code = 108
char = e;code = 101
char = x;code = 120
char = ;code = 32
char = v;code = 118
char = i;code = 105
char = r;code = 114
char = u;code = 117
char = s;code = 115
char = ;code = 32
char = e;code = 101
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = p;code = 112
char = h;code = 104
char = a;code = 97
char = l;code = 108
char = i;code = 105
char = t;code = 116
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = m;code = 109
char = p;code = 112
char = l;code = 108
char = i;code = 105
char = c;code = 99
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = b;code = 98
char = y;code = 121
char = ;code = 32
char = s;code = 115
char = u;code = 117
char = b;code = 98
char = a;code = 97
char = r;code = 114
char = a;code = 97
char = c;code = 99
char = h;code = 104
char = n;code = 110
char = o;code = 111
char = i;code = 105
char = d;code = 100
char = ;code = 32
char = b;code = 98
char = l;code = 108
char = e;code = 101
char = e;code = 101
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char = i;code = 105
char = n;code = 110
char = g;code = 103
char = .;code = 46
result sql = INTRODUCTION : Histopathologically, herpes simplex virus type 1 causes hemorrhagic necrosis. Overt hemorrhage is infrequent in herpes simplex virus encephalitis but can lead to poor outcomes. This report describes a successfully treated case of herpes simplex virus encephalitis associated with subarachnoid bleeding in which real-time polymerase chain reaction was useful for diagnosis.
CASE PRESENTATION : A 30-year-old previously healthy Japanese woman who had fever and headache for five days presented with disorganised speech, unusual behavior and delusional thinking. Real-time polymerase chain reaction amplification of herpes simplex virus type 1 in cerebrospinal fluid was positive (38,000 copies/mL) and antivirus treatment was started. During the course of her illness, the level of her consciousness decreased in association with desaturation and tachycardia. Thrombosis of the right pulmonary artery trunk with pulmonary embolism was evident on enhanced chest computed tomography. In addition, cranial computed tomography revealed subarachnoid and intraventricular bleeding. Intravenous heparin (12,000 U/day) was started and the dose was adjusted according to the activated partial thromboplastin time for about a month (maximum dose of heparin, 20,400 U/day). After the treatments, her Glasgow coma score increased and the thrombosis of the pulmonary artery trunk had disappeared.
CONCLUSIONS : The present case raises the question of whether anticoagulant treatment is safe in patients with herpes simplex virus encephalitis complicated by subarachnoid bleeding.
Publication: J Med Case Rep 2010 ;4:310. :doi: 10.1186/1752-1947-4-310.
Publication Date: 2010
Study Author(s): Tonomura, Yasuyo;Kataoka, Hiroshi;Yata, Noritaka;Kawahara, Makoto;Okuchi, Kazuo;Ueno, Satoshi;
Institution: Department of Neurology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan. [email protected].
Shortcut link to this study:
Publication Date: 2010
Study Author(s): Tonomura, Yasuyo;Kataoka, Hiroshi;Yata, Noritaka;Kawahara, Makoto;Okuchi, Kazuo;Ueno, Satoshi;
Institution: Department of Neurology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan. [email protected].
Shortcut link to this study:
INTRODUCTION : Histopathologically, herpes simplex virus type 1 causes hemorrhagic necrosis. Overt hemorrhage is infrequent in herpes simplex virus encephalitis but can lead to poor outcomes. This report describes a successfully treated case of herpes simplex virus encephalitis associated with subarachnoid bleeding in which real-time polymerase chain reaction was useful for diagnosis.
CASE PRESENTATION : A 30-year-old previously healthy Japanese woman who had fever and headache for five days presented with disorganised speech, unusual behavior and delusional thinking. Real-time polymerase chain reaction amplification of herpes simplex virus type 1 in cerebrospinal fluid was positive (38,000 copies/mL) and antivirus treatment was started. During the course of her illness, the level of her consciousness decreased in association with desaturation and tachycardia. Thrombosis of the right pulmonary artery trunk with pulmonary embolism was evident on enhanced chest computed tomography. In addition, cranial computed tomography revealed subarachnoid and intraventricular bleeding. Intravenous heparin (12,000 U/day) was started and the dose was adjusted according to the activated partial thromboplastin time for about a month (maximum dose of heparin, 20,400 U/day). After the treatments, her Glasgow coma score increased and the thrombosis of the pulmonary artery trunk had disappeared.
CONCLUSIONS : The present case raises the question of whether anticoagulant treatment is safe in patients with herpes simplex virus encephalitis complicated by subarachnoid bleeding.
CASE PRESENTATION : A 30-year-old previously healthy Japanese woman who had fever and headache for five days presented with disorganised speech, unusual behavior and delusional thinking. Real-time polymerase chain reaction amplification of herpes simplex virus type 1 in cerebrospinal fluid was positive (38,000 copies/mL) and antivirus treatment was started. During the course of her illness, the level of her consciousness decreased in association with desaturation and tachycardia. Thrombosis of the right pulmonary artery trunk with pulmonary embolism was evident on enhanced chest computed tomography. In addition, cranial computed tomography revealed subarachnoid and intraventricular bleeding. Intravenous heparin (12,000 U/day) was started and the dose was adjusted according to the activated partial thromboplastin time for about a month (maximum dose of heparin, 20,400 U/day). After the treatments, her Glasgow coma score increased and the thrombosis of the pulmonary artery trunk had disappeared.
CONCLUSIONS : The present case raises the question of whether anticoagulant treatment is safe in patients with herpes simplex virus encephalitis complicated by subarachnoid bleeding.
PMID: 20860812
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