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char = o;code = 111
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char = i;code = 105
char = s;code = 115
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char = d;code = 100
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char = ;code = 32
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char = o;code = 111
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char = o;code = 111
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char = B;code = 66
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result sql = To describe the structural changes in the pituitary gland and accompanying pituitary hormonal problems in patients with Bardet-Biedl syndrome (BBS), 11 patients with BBS (median age: 12.8 years, range: 2.5-17.8 years; four boys and seven girls) have been examined for the anomalies of the pituitary region detected by MRI. Accompanying clinical, biochemical, and hormonal profiles concerning the pituitary function of the patients have also been investigated. We have found a high incidence of pituitary anomalies on MRI (63%) and a considerable percentage of hormonal derangements (45%) accompanying these. Among the structural pituitary abnormalities, tumoral changes (n=2), hypoplastic hypophysis, and/or sella (n=4) and rathke cleft cyst (n=2) were detected, whereas disturbances of the pituitary hormones such as growth hormone deficiency, hyperprolactinemia, hypogonadotrophic hypogonadism, and central precocious puberty accompanied the pituitary anomalies in these patients. Pituitary abnormalities and pituitary hormonal dysfunction are common findings and, therefore, should be included in the diagnostic criteria of BBS.
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char = o;code = 111
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char = i;code = 105
char = c;code = 99
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
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char = o;code = 111
char = r;code = 114
char = m;code = 109
char = o;code = 111
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char = ;code = 32
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char = v;code = 118
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char = l;code = 108
char = u;code = 117
char = a;code = 97
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char = o;code = 111
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = p;code = 112
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char = t;code = 116
char = u;code = 117
char = i;code = 105
char = t;code = 116
char = a;code = 97
char = r;code = 114
char = y;code = 121
char = ;code = 32
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char = o;code = 111
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char = m;code = 109
char = a;code = 97
char = l;code = 108
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char = o;code = 111
char = m;code = 109
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result sql = Radiologic and hormonal evaluation of pituitary abnormalities in patients with Bardet-Biedl syndrome.
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result sql = To describe the structural changes in the pituitary gland and accompanying pituitary hormonal problems in patients with Bardet-Biedl syndrome (BBS), 11 patients with BBS (median age: 12.8 years, range: 2.5-17.8 years; four boys and seven girls) have been examined for the anomalies of the pituitary region detected by MRI. Accompanying clinical, biochemical, and hormonal profiles concerning the pituitary function of the patients have also been investigated. We have found a high incidence of pituitary anomalies on MRI (63%) and a considerable percentage of hormonal derangements (45%) accompanying these. Among the structural pituitary abnormalities, tumoral changes (n=2), hypoplastic hypophysis, and/or sella (n=4) and rathke cleft cyst (n=2) were detected, whereas disturbances of the pituitary hormones such as growth hormone deficiency, hyperprolactinemia, hypogonadotrophic hypogonadism, and central precocious puberty accompanied the pituitary anomalies in these patients. Pituitary abnormalities and pituitary hormonal dysfunction are common findings and, therefore, should be included in the diagnostic criteria of BBS.
Publication: Clin. Dysmorphol. 2011 Jan ;20(1)::26-31. :doi: 10.1097/MCD.0b013e32833fd528.
Publication Date: 2011 Jan
Study Author(s): Guran, Tulay;Ekinci, Gazanfer;Atay, Zeynep;Turan, Serap;Akcay, Teoman;Bereket, Abdullah;
Institution: Department of Pediatric Endocrinology, Faculty of Medicine, Marmara University, Altunizade, Istanbul, Turkey. [email protected]
Shortcut link to this study:
Publication Date: 2011 Jan
Study Author(s): Guran, Tulay;Ekinci, Gazanfer;Atay, Zeynep;Turan, Serap;Akcay, Teoman;Bereket, Abdullah;
Institution: Department of Pediatric Endocrinology, Faculty of Medicine, Marmara University, Altunizade, Istanbul, Turkey. [email protected]
Shortcut link to this study:
To describe the structural changes in the pituitary gland and accompanying pituitary hormonal problems in patients with Bardet-Biedl syndrome (BBS), 11 patients with BBS (median age: 12.8 years, range: 2.5-17.8 years; four boys and seven girls) have been examined for the anomalies of the pituitary region detected by MRI. Accompanying clinical, biochemical, and hormonal profiles concerning the pituitary function of the patients have also been investigated. We have found a high incidence of pituitary anomalies on MRI (63%) and a considerable percentage of hormonal derangements (45%) accompanying these. Among the structural pituitary abnormalities, tumoral changes (n=2), hypoplastic hypophysis, and/or sella (n=4) and rathke cleft cyst (n=2) were detected, whereas disturbances of the pituitary hormones such as growth hormone deficiency, hyperprolactinemia, hypogonadotrophic hypogonadism, and central precocious puberty accompanied the pituitary anomalies in these patients. Pituitary abnormalities and pituitary hormonal dysfunction are common findings and, therefore, should be included in the diagnostic criteria of BBS.
PMID: 20966747
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