|
|
char = C;code = 67
char = o;code = 111
char = r;code = 114
char = r;code = 114
char = e;code = 101
char = l;code = 108
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char = i;code = 105
char = o;code = 111
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char = s;code = 115
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char = o;code = 111
char = g;code = 103
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char = a;code = 97
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char = r;code = 114
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char = c;code = 99
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char = g;code = 103
char = a;code = 97
char = s;code = 115
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = t;code = 116
char = i;code = 105
char = s;code = 115
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char = i;code = 105
char = n;code = 110
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char = g;code = 103
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char = s;code = 115
char = t;code = 116
char = r;code = 114
char = o;code = 111
char = e;code = 101
char = s;code = 115
char = o;code = 111
char = p;code = 112
char = h;code = 104
char = a;code = 97
char = g;code = 103
char = e;code = 101
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = f;code = 102
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char = x;code = 120
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char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = :;code = 58
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = m;code = 109
char = a;code = 97
char = t;code = 116
char = c;code = 99
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char = e;code = 101
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char = a;code = 97
char = i;code = 105
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char = ;code = 32
char = s;code = 115
char = t;code = 116
char = u;code = 117
char = d;code = 100
char = y;code = 121
char = .;code = 46
result sql = Correlation of serum pepsinogens and gastrin-17 with atrophic gastritis in gastroesophageal reflux patients: a matched-pairs study.
Correlation of serum pepsinogens and gastrin-17 with atrophic gastritis in gastroesophageal reflux patients: a matched-pairs study.char = <;code = 60
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char = A;code = 65
char = C;code = 67
char = K;code = 75
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char = R;code = 82
char = O;code = 79
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char = N;code = 78
char = D;code = 68
char = ;code = 32
char = A;code = 65
char = N;code = 78
char = D;code = 68
char = ;code = 32
char = A;code = 65
char = I;code = 73
char = M;code = 77
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
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char = A;code = 65
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char = l;code = 108
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char = o;code = 111
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char = i;code = 105
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char = m;code = 109
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char = (;code = 40
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char = l;code = 108
char = );code = 41
char = ;code = 32
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char = o;code = 111
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char = t;code = 116
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char = o;code = 111
char = n;code = 110
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char = i;code = 105
char = c;code = 99
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char = g;code = 103
char = a;code = 97
char = s;code = 115
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = t;code = 116
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = h;code = 104
char = a;code = 97
char = s;code = 115
char = ;code = 32
char = b;code = 98
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char = ,;code = 44
char = ;code = 32
char = b;code = 98
char = a;code = 97
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char = e;code = 101
char = d;code = 100
char = ;code = 32
char = o;code = 111
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char = ;code = 32
char = s;code = 115
char = e;code = 101
char = r;code = 114
char = u;code = 117
char = m;code = 109
char = ;code = 32
char = p;code = 112
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char = p;code = 112
char = s;code = 115
char = i;code = 105
char = n;code = 110
char = o;code = 111
char = g;code = 103
char = e;code = 101
char = n;code = 110
char = -;code = 45
char = I;code = 73
char = ,;code = 44
char = ;code = 32
char = g;code = 103
char = a;code = 97
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char = t;code = 116
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char = H;code = 72
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char = b;code = 98
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char = e;code = 101
char = r;code = 114
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char = p;code = 112
char = y;code = 121
char = l;code = 108
char = o;code = 111
char = r;code = 114
char = i;code = 105
char = ;code = 32
char = (;code = 40
char = H;code = 72
char = .;code = 46
char = ;code = 32
char = p;code = 112
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char = l;code = 108
char = o;code = 111
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char = i;code = 105
char = );code = 41
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char = a;code = 97
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char = i;code = 105
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char = i;code = 105
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char = s;code = 115
char = .;code = 46
char = ;code = 32
char = T;code = 84
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = a;code = 97
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char = m;code = 109
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char = o;code = 111
char = f;code = 102
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char = t;code = 116
char = h;code = 104
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char = p;code = 112
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char = m;code = 109
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char = k;code = 107
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char = g;code = 103
char = a;code = 97
char = s;code = 115
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = c;code = 99
char = ;code = 32
char = a;code = 97
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char = r;code = 114
char = o;code = 111
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char = h;code = 104
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char = i;code = 105
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char = g;code = 103
char = a;code = 97
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char = t;code = 116
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char = a;code = 97
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char = x;code = 120
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char = d;code = 100
char = i;code = 105
char = s;code = 115
char = e;code = 101
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = G;code = 71
char = E;code = 69
char = R;code = 82
char = D;code = 68
char = );code = 41
char = ;code = 32
char = p;code = 112
char = a;code = 97
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char = i;code = 105
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char = .;code = 46
char = <;code = 60
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char = <;code = 60
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char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
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char = M;code = 77
char = E;code = 69
char = T;code = 84
char = H;code = 72
char = O;code = 79
char = D;code = 68
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = T;code = 84
char = h;code = 104
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char = b;code = 98
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char = P;code = 80
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char = G;code = 71
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result sql = BACKGROUND AND AIM : An algorithm (GastroPanel) for the non-invasive diagnosis of atrophic gastritis has been previously proposed, based on serum pepsinogen-I, gastrin-17, and Helicobacter pylori (H. pylori) antibodies. The aim of the present study was to evaluate whether serum markers correlate with and predict gastric atrophy in gastroesophageal reflux disease (GERD) patients.
METHODS : The baseline data of the prospective ProGERD study, a study on the long-term course of GERD (n=6215 patients), served to select patients with atrophic gastritis diagnosed in biopsies from gastric antrum and corpus, and control cases without atrophy. A total of 208 pairs were matched for age, sex, GERD status (erosive vs non-erosive), presence of Barrett's esophagus, and histological H. pylori status were retrieved. Serum pepsinogen-I, gastrin-17, and H. pylori antibodies were determined using specific enzyme immunoassays.
RESULTS : A significant negative correlation was found between the degree of corpus atrophy and the level of serum pepsinogen-I. A previously-reported negative correlation between the degree of antral atrophy and serum gastrin-17 could not be confirmed. The low sensitivity (0.32) and specificity (0.70) of the GastroPanel algorithm were mainly due to over diagnosis and under diagnosis of advanced atrophy in the antrum.
CONCLUSION : The diagnostic validity of the GastroPanel algorithm to diagnose gastric atrophy non-invasively is not sufficient for general use in GERD patients.
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result sql = Correlation of serum pepsinogens and gastrin-17 with atrophic gastritis in gastroesophageal reflux patients: a matched-pairs study.
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result sql = BACKGROUND AND AIM : An algorithm (GastroPanel) for the non-invasive diagnosis of atrophic gastritis has been previously proposed, based on serum pepsinogen-I, gastrin-17, and Helicobacter pylori (H. pylori) antibodies. The aim of the present study was to evaluate whether serum markers correlate with and predict gastric atrophy in gastroesophageal reflux disease (GERD) patients.
METHODS : The baseline data of the prospective ProGERD study, a study on the long-term course of GERD (n=6215 patients), served to select patients with atrophic gastritis diagnosed in biopsies from gastric antrum and corpus, and control cases without atrophy. A total of 208 pairs were matched for age, sex, GERD status (erosive vs non-erosive), presence of Barrett's esophagus, and histological H. pylori status were retrieved. Serum pepsinogen-I, gastrin-17, and H. pylori antibodies were determined using specific enzyme immunoassays.
RESULTS : A significant negative correlation was found between the degree of corpus atrophy and the level of serum pepsinogen-I. A previously-reported negative correlation between the degree of antral atrophy and serum gastrin-17 could not be confirmed. The low sensitivity (0.32) and specificity (0.70) of the GastroPanel algorithm were mainly due to over diagnosis and under diagnosis of advanced atrophy in the antrum.
CONCLUSION : The diagnostic validity of the GastroPanel algorithm to diagnose gastric atrophy non-invasively is not sufficient for general use in GERD patients.
Publication: J. Gastroenterol. Hepatol. 2011 Jan ;26(1)::82-9. :doi: 10.1111/j.1440-1746.2010.06413.x.
Publication Date: 2011 Jan
Study Author(s): Peitz, Ulrich;Wex, Thomas;Vieth, Michael;Stolte, Manfred;Willich, Stefan;Labenz, Joachim;Jaspersen, Daniel;Lind, Tore;Malfertheiner, Peter;
Institution: Department of Gastroenterology, Hepatology, and Infectious Diseases, University of Magdeburg, Magdeburg, Germany.
Shortcut link to this study:
Publication Date: 2011 Jan
Study Author(s): Peitz, Ulrich;Wex, Thomas;Vieth, Michael;Stolte, Manfred;Willich, Stefan;Labenz, Joachim;Jaspersen, Daniel;Lind, Tore;Malfertheiner, Peter;
Institution: Department of Gastroenterology, Hepatology, and Infectious Diseases, University of Magdeburg, Magdeburg, Germany.
Shortcut link to this study:
BACKGROUND AND AIM : An algorithm (GastroPanel) for the non-invasive diagnosis of atrophic gastritis has been previously proposed, based on serum pepsinogen-I, gastrin-17, and Helicobacter pylori (H. pylori) antibodies. The aim of the present study was to evaluate whether serum markers correlate with and predict gastric atrophy in gastroesophageal reflux disease (GERD) patients.
METHODS : The baseline data of the prospective ProGERD study, a study on the long-term course of GERD (n=6215 patients), served to select patients with atrophic gastritis diagnosed in biopsies from gastric antrum and corpus, and control cases without atrophy. A total of 208 pairs were matched for age, sex, GERD status (erosive vs non-erosive), presence of Barrett's esophagus, and histological H. pylori status were retrieved. Serum pepsinogen-I, gastrin-17, and H. pylori antibodies were determined using specific enzyme immunoassays.
RESULTS : A significant negative correlation was found between the degree of corpus atrophy and the level of serum pepsinogen-I. A previously-reported negative correlation between the degree of antral atrophy and serum gastrin-17 could not be confirmed. The low sensitivity (0.32) and specificity (0.70) of the GastroPanel algorithm were mainly due to over diagnosis and under diagnosis of advanced atrophy in the antrum.
CONCLUSION : The diagnostic validity of the GastroPanel algorithm to diagnose gastric atrophy non-invasively is not sufficient for general use in GERD patients.
METHODS : The baseline data of the prospective ProGERD study, a study on the long-term course of GERD (n=6215 patients), served to select patients with atrophic gastritis diagnosed in biopsies from gastric antrum and corpus, and control cases without atrophy. A total of 208 pairs were matched for age, sex, GERD status (erosive vs non-erosive), presence of Barrett's esophagus, and histological H. pylori status were retrieved. Serum pepsinogen-I, gastrin-17, and H. pylori antibodies were determined using specific enzyme immunoassays.
RESULTS : A significant negative correlation was found between the degree of corpus atrophy and the level of serum pepsinogen-I. A previously-reported negative correlation between the degree of antral atrophy and serum gastrin-17 could not be confirmed. The low sensitivity (0.32) and specificity (0.70) of the GastroPanel algorithm were mainly due to over diagnosis and under diagnosis of advanced atrophy in the antrum.
CONCLUSION : The diagnostic validity of the GastroPanel algorithm to diagnose gastric atrophy non-invasively is not sufficient for general use in GERD patients.
PMID: 21175799
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