|
|
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result sql = Screening of anti-inflammatory and antipyretic activity of Vitex leucoxylon Linn.
Screening of anti-inflammatory and antipyretic activity of Vitex leucoxylon Linn.char = <;code = 60
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result sql = OBJECTIVE : This study was designed to evaluate the anti-inflammatory and antipyretic activity of ethyl acetate extract of Vitex leucoxylon Linn. in various animal experimental models.
MATERIALS AND METHODS : Ethyl acetate extract of V. leucoxylon Linn. evaluated for anti-inflammatory activity in carrageenan, mediator-induced rat paw edema, and cotton pellet-induced granuloma model. The antipyretic activity was evaluated by yeast-induced pyrexia model.
RESULTS : Single administration of the ethyl acetate extract of V. leucoxylon Linn. at dose of 500 mg/kg p.o. showed significant (P < 0.001) inhibition of rat paw edema. The ethyl acetate extract showed significant antipyretic activity in brewer yeast-induced pyrexia in rats throughout the observation period of 4 h.
CONCLUSION : This study shows that ethyl acetate extract of V. leucoxylon Linn. has significant anti-inflammatory and antipyretic activity.
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result sql = Screening of anti-inflammatory and antipyretic activity of Vitex leucoxylon Linn.
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char = ;code = 32
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char = p;code = 112
char = y;code = 121
char = r;code = 114
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result sql = OBJECTIVE : This study was designed to evaluate the anti-inflammatory and antipyretic activity of ethyl acetate extract of Vitex leucoxylon Linn. in various animal experimental models.
MATERIALS AND METHODS : Ethyl acetate extract of V. leucoxylon Linn. evaluated for anti-inflammatory activity in carrageenan, mediator-induced rat paw edema, and cotton pellet-induced granuloma model. The antipyretic activity was evaluated by yeast-induced pyrexia model.
RESULTS : Single administration of the ethyl acetate extract of V. leucoxylon Linn. at dose of 500 mg/kg p.o. showed significant (P < 0.001) inhibition of rat paw edema. The ethyl acetate extract showed significant antipyretic activity in brewer yeast-induced pyrexia in rats throughout the observation period of 4 h.
CONCLUSION : This study shows that ethyl acetate extract of V. leucoxylon Linn. has significant anti-inflammatory and antipyretic activity.
Publication: Indian J Pharmacol 2010 Dec ;42(6)::409-11.
Publication Date: 2010 Dec
Study Author(s): Shukla, Padmini;Shukla, P;Mishra, S B;Gopalakrishna, B;
Institution: Pranveer Singh Institute of Technology, Kanpur, India.
Shortcut link to this study:
Publication Date: 2010 Dec
Study Author(s): Shukla, Padmini;Shukla, P;Mishra, S B;Gopalakrishna, B;
Institution: Pranveer Singh Institute of Technology, Kanpur, India.
Shortcut link to this study:
OBJECTIVE : This study was designed to evaluate the anti-inflammatory and antipyretic activity of ethyl acetate extract of Vitex leucoxylon Linn. in various animal experimental models.
MATERIALS AND METHODS : Ethyl acetate extract of V. leucoxylon Linn. evaluated for anti-inflammatory activity in carrageenan, mediator-induced rat paw edema, and cotton pellet-induced granuloma model. The antipyretic activity was evaluated by yeast-induced pyrexia model.
RESULTS : Single administration of the ethyl acetate extract of V. leucoxylon Linn. at dose of 500 mg/kg p.o. showed significant (P < 0.001) inhibition of rat paw edema. The ethyl acetate extract showed significant antipyretic activity in brewer yeast-induced pyrexia in rats throughout the observation period of 4 h.
CONCLUSION : This study shows that ethyl acetate extract of V. leucoxylon Linn. has significant anti-inflammatory and antipyretic activity.
MATERIALS AND METHODS : Ethyl acetate extract of V. leucoxylon Linn. evaluated for anti-inflammatory activity in carrageenan, mediator-induced rat paw edema, and cotton pellet-induced granuloma model. The antipyretic activity was evaluated by yeast-induced pyrexia model.
RESULTS : Single administration of the ethyl acetate extract of V. leucoxylon Linn. at dose of 500 mg/kg p.o. showed significant (P < 0.001) inhibition of rat paw edema. The ethyl acetate extract showed significant antipyretic activity in brewer yeast-induced pyrexia in rats throughout the observation period of 4 h.
CONCLUSION : This study shows that ethyl acetate extract of V. leucoxylon Linn. has significant anti-inflammatory and antipyretic activity.
PMID: 21189917
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