|
|
char = A;code = 65
char = r;code = 114
char = t;code = 116
char = e;code = 101
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char = u;code = 117
char = l;code = 108
char = u;code = 117
char = s;code = 115
char = ;code = 32
char = L;code = 76
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char = r;code = 114
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char = e;code = 101
char = ,;code = 44
char = ;code = 32
char = c;code = 99
char = h;code = 104
char = e;code = 101
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char = l;code = 108
char = ;code = 32
char = c;code = 99
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char = m;code = 109
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char = c;code = 99
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char = l;code = 108
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char = s;code = 115
char = a;code = 97
char = f;code = 102
char = e;code = 101
char = t;code = 116
char = y;code = 121
char = .;code = 46
result sql = Artemisia dracunculus L. (tarragon): a critical review of its traditional use, chemical composition, pharmacology, and safety.
Artemisia dracunculus L. (tarragon): a critical review of its traditional use, chemical composition, pharmacology, and safety.char = A;code = 65
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char = t;code = 116
char = e;code = 101
char = m;code = 109
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char = c;code = 99
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char = n;code = 110
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char = u;code = 117
char = l;code = 108
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char = s;code = 115
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char = ;code = 32
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char = r;code = 114
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char = ;code = 32
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char = (;code = 40
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result sql = Artemisia dracunculus L. (tarragon) has a long history of use as a spice and remedy. Two well-described "cultivars" (Russian and French) are used widely and differ in ploidy level, morphology, and chemistry. Key biologically active secondary metabolites are essential oils (0.15-3.1%), coumarins (>1%), flavonoids, and phenolcarbonic acids. In vivo studies mainly in rodents, particularly from Russian sources, highlight potential anti-inflammatory, hepatoprotective, and antihyperglycemic effects. Despite concerns about the toxic effects of two of its main constituents, estragole (up to 82%) and methyleugenol (up to 39%), no acute toxicity or mutagenic activity has been reported at doses relevant for human consumption. Water extracts of A. dracunculus contain very low amounts of estragole and methyleugenol and, therefore, are considered to pose a very limited risk. Overall, a stronger focus on clinical studies and precise taxonomic and phytochemical definition of the source material will be essential for future research efforts.
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char = a;code = 97
char = f;code = 102
char = e;code = 101
char = t;code = 116
char = y;code = 121
char = .;code = 46
result sql = Artemisia dracunculus L. (tarragon): a critical review of its traditional use, chemical composition, pharmacology, and safety.
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result sql = Artemisia dracunculus L. (tarragon) has a long history of use as a spice and remedy. Two well-described "cultivars" (Russian and French) are used widely and differ in ploidy level, morphology, and chemistry. Key biologically active secondary metabolites are essential oils (0.15-3.1%), coumarins (>1%), flavonoids, and phenolcarbonic acids. In vivo studies mainly in rodents, particularly from Russian sources, highlight potential anti-inflammatory, hepatoprotective, and antihyperglycemic effects. Despite concerns about the toxic effects of two of its main constituents, estragole (up to 82%) and methyleugenol (up to 39%), no acute toxicity or mutagenic activity has been reported at doses relevant for human consumption. Water extracts of A. dracunculus contain very low amounts of estragole and methyleugenol and, therefore, are considered to pose a very limited risk. Overall, a stronger focus on clinical studies and precise taxonomic and phytochemical definition of the source material will be essential for future research efforts.
Publication: J. Agric. Food Chem. 2011 Nov 9 ;59(21)::11367-84. :doi: 10.1021/jf202277w.
Publication Date: 2011 Nov 9
Study Author(s): Obolskiy, Dmitry;Pischel, Ivo;Feistel, Bjoern;Glotov, Nikolay;Heinrich, Michael;
Institution: Center for Pharmacognosy and Phytotherapy, The School of Pharmacy (University of London), 29-39 Brunswick Square, London WC1N 1AX, United Kingdom.
Shortcut link to this study:
Publication Date: 2011 Nov 9
Study Author(s): Obolskiy, Dmitry;Pischel, Ivo;Feistel, Bjoern;Glotov, Nikolay;Heinrich, Michael;
Institution: Center for Pharmacognosy and Phytotherapy, The School of Pharmacy (University of London), 29-39 Brunswick Square, London WC1N 1AX, United Kingdom.
Shortcut link to this study:
Artemisia dracunculus L. (tarragon) has a long history of use as a spice and remedy. Two well-described "cultivars" (Russian and French) are used widely and differ in ploidy level, morphology, and chemistry. Key biologically active secondary metabolites are essential oils (0.15-3.1%), coumarins (>1%), flavonoids, and phenolcarbonic acids. In vivo studies mainly in rodents, particularly from Russian sources, highlight potential anti-inflammatory, hepatoprotective, and antihyperglycemic effects. Despite concerns about the toxic effects of two of its main constituents, estragole (up to 82%) and methyleugenol (up to 39%), no acute toxicity or mutagenic activity has been reported at doses relevant for human consumption. Water extracts of A. dracunculus contain very low amounts of estragole and methyleugenol and, therefore, are considered to pose a very limited risk. Overall, a stronger focus on clinical studies and precise taxonomic and phytochemical definition of the source material will be essential for future research efforts.
PMID: 21942448
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