|
|
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result sql = Capsaicin desensitization induces atrophy of brown adipose tissue in rats.
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char = o;code = 111
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char = m;code = 109
char = a;code = 97
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char = f;code = 102
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char = ;code = 32
char = n;code = 110
char = o;code = 111
char = r;code = 114
char = m;code = 109
char = o;code = 111
char = t;code = 116
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char = e;code = 101
char = r;code = 114
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char = ;code = 32
char = b;code = 98
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char = ;code = 32
char = d;code = 100
char = a;code = 97
char = y;code = 121
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char = c;code = 99
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char = d;code = 100
char = ;code = 32
char = e;code = 101
char = x;code = 120
char = p;code = 112
char = o;code = 111
char = s;code = 115
char = u;code = 117
char = r;code = 114
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char = ;code = 32
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char = c;code = 99
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char = o;code = 111
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char = ;code = 32
char = t;code = 116
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char = y;code = 121
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char = d;code = 100
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char = r;code = 114
char = m;code = 109
char = o;code = 111
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char = e;code = 101
char = s;code = 115
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char = i;code = 105
char = n;code = 110
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
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char = r;code = 114
char = ;code = 32
char = b;code = 98
char = l;code = 108
char = o;code = 111
char = o;code = 111
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char = ;code = 32
char = w;code = 119
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char = o;code = 111
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char = m;code = 109
char = a;code = 97
char = l;code = 108
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char = ;code = 32
char = I;code = 73
char = t;code = 116
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char = i;code = 105
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char = s;code = 115
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char = g;code = 103
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char = e;code = 101
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char = h;code = 104
char = a;code = 97
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char = t;code = 116
char = h;code = 104
char = e;code = 101
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char = d;code = 100
char = e;code = 101
char = p;code = 112
char = l;code = 108
char = e;code = 101
char = t;code = 116
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char = o;code = 111
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char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = s;code = 115
char = e;code = 101
char = n;code = 110
char = s;code = 115
char = o;code = 111
char = r;code = 114
char = y;code = 121
char = ;code = 32
char = n;code = 110
char = e;code = 101
char = u;code = 117
char = r;code = 114
char = o;code = 111
char = p;code = 112
char = e;code = 101
char = p;code = 112
char = t;code = 116
char = i;code = 105
char = d;code = 100
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = B;code = 66
char = A;code = 65
char = T;code = 84
char = ;code = 32
char = p;code = 112
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = u;code = 117
char = m;code = 109
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = b;code = 98
char = e;code = 101
char = ;code = 32
char = b;code = 98
char = r;code = 114
char = o;code = 111
char = u;code = 117
char = g;code = 103
char = h;code = 104
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char = ;code = 32
char = a;code = 97
char = b;code = 98
char = o;code = 111
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char = t;code = 116
char = ;code = 32
char = b;code = 98
char = y;code = 121
char = ;code = 32
char = C;code = 67
char = a;code = 97
char = p;code = 112
char = -;code = 45
char = D;code = 68
char = e;code = 101
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char = ;code = 32
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = u;code = 117
char = l;code = 108
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = e;code = 101
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = l;code = 108
char = o;code = 111
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char = s;code = 115
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char = o;code = 111
char = f;code = 102
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char = a;code = 97
char = ;code = 32
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char = p;code = 112
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char = i;code = 105
char = c;code = 99
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char = i;code = 105
char = n;code = 110
char = f;code = 102
char = l;code = 108
char = u;code = 117
char = e;code = 101
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = ;code = 32
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = m;code = 109
char = i;code = 105
char = t;code = 116
char = o;code = 111
char = c;code = 99
char = h;code = 104
char = o;code = 111
char = n;code = 110
char = d;code = 100
char = r;code = 114
char = i;code = 105
char = o;code = 111
char = g;code = 103
char = e;code = 101
char = n;code = 110
char = e;code = 101
char = s;code = 115
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = B;code = 66
char = A;code = 65
char = T;code = 84
char = ;code = 32
char = o;code = 111
char = r;code = 114
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = l;code = 108
char = a;code = 97
char = c;code = 99
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = h;code = 104
char = i;code = 105
char = b;code = 98
char = i;code = 105
char = t;code = 116
char = o;code = 111
char = r;code = 114
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char = ;code = 32
char = i;code = 105
char = n;code = 110
char = f;code = 102
char = l;code = 108
char = u;code = 117
char = e;code = 101
char = n;code = 110
char = c;code = 99
char = e;code = 101
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char = o;code = 111
char = n;code = 110
char = ;code = 32
char = m;code = 109
char = i;code = 105
char = t;code = 116
char = o;code = 111
char = c;code = 99
char = h;code = 104
char = o;code = 111
char = n;code = 110
char = d;code = 100
char = r;code = 114
char = i;code = 105
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = b;code = 98
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = k;code = 107
char = d;code = 100
char = o;code = 111
char = w;code = 119
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char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = B;code = 66
char = A;code = 65
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char = ;code = 32
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char = d;code = 100
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char = l;code = 108
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char = d;code = 100
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char = f;code = 102
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char = A;code = 65
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char = ;code = 32
char = i;code = 105
char = n;code = 110
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char = r;code = 114
char = a;code = 97
char = t;code = 116
char = s;code = 115
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char = l;code = 108
char = i;code = 105
char = v;code = 118
char = i;code = 105
char = n;code = 110
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char = m;code = 109
char = u;code = 117
char = l;code = 108
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
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char = b;code = 98
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char = d;code = 100
char = i;code = 105
char = e;code = 101
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char = B;code = 66
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char = T;code = 84
char = R;code = 82
char = A;code = 65
char = C;code = 67
char = T;code = 84
char = ;code = 32
char = T;code = 84
char = R;code = 82
char = U;code = 85
char = N;code = 78
char = C;code = 67
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char = T;code = 84
char = E;code = 69
char = D;code = 68
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char = A;code = 65
char = T;code = 84
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char = 2;code = 50
char = 5;code = 53
char = 0;code = 48
char = ;code = 32
char = W;code = 87
char = O;code = 79
char = R;code = 82
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result sql = Interscapular brown adipose tissue (BAT) of capsaicin-desensitized (Cap-Des) rats is atrophied, having a lower wet weight, a reduced total protein content, and as little as 10% of the normal content of uncoupling protein (UCP). Because the mitochondrial concentration of UCP, relative to other mitochondrial proteins, is not altered in Cap-Des rats, it is concluded that most of the mitochondria of BAT of Cap-Des rats have been lost. Consistent with this interpretation is a reduction of almost 40% of the overall thermogenic response to infused norepinephrine by anesthetized Cap-Des rats. Feeding a palatable diet had a delayed thermogenic effect and no trophic effect on BAT of Cap-Des rats. Food selection and intake were normal in Cap-Des rats, and diet-induced weight gain was the same as in control rats. Exposure of Cap-Des rats to cold for 1 or 7 days exerted a normal thermogenic effect on BAT but a delayed trophic effect. The cold-induced increase in thyroxine 5'-deiodinase in BAT occurred normally. Cap-Des rats were hypothermic at 1 day but normothermic by 7 days of cold exposure. The concentration of thyroid hormones in their blood was normal. It is suggested that the depletion of sensory neuropeptides in BAT presumed to be brought about by Cap-Des results either in loss of a trophic influence on mitochondriogenesis in BAT or in lack of an inhibitory influence on mitochondrial breakdown in BAT and leads to atrophy of BAT in rats living at 26 degrees C and an impaired response to stimulation by diet.(ABSTRACT TRUNCATED AT 250 WORDS)
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char = i;code = 105
char = c;code = 99
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = d;code = 100
char = e;code = 101
char = s;code = 115
char = e;code = 101
char = n;code = 110
char = s;code = 115
char = i;code = 105
char = t;code = 116
char = i;code = 105
char = z;code = 122
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = d;code = 100
char = u;code = 117
char = c;code = 99
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = a;code = 97
char = t;code = 116
char = r;code = 114
char = o;code = 111
char = p;code = 112
char = h;code = 104
char = y;code = 121
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = b;code = 98
char = r;code = 114
char = o;code = 111
char = w;code = 119
char = n;code = 110
char = ;code = 32
char = a;code = 97
char = d;code = 100
char = i;code = 105
char = p;code = 112
char = o;code = 111
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = i;code = 105
char = s;code = 115
char = s;code = 115
char = u;code = 117
char = e;code = 101
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = s;code = 115
char = .;code = 46
result sql = Capsaicin desensitization induces atrophy of brown adipose tissue in rats.
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char = ;code = 32
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char = t;code = 116
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char = a;code = 97
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char = r;code = 114
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char = u;code = 117
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char = e;code = 101
char = d;code = 100
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char = t;code = 116
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char = t;code = 116
char = a;code = 97
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char = r;code = 114
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char = ;code = 32
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char = a;code = 97
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char = l;code = 108
char = i;code = 105
char = t;code = 116
char = t;code = 116
char = l;code = 108
char = e;code = 101
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char = a;code = 97
char = s;code = 115
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char = 1;code = 49
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char = %;code = 37
char = ;code = 32
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char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
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char = a;code = 97
char = l;code = 108
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char = c;code = 99
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char = e;code = 101
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = u;code = 117
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char = r;code = 114
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char = t;code = 116
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char = ;code = 32
char = (;code = 40
char = U;code = 85
char = C;code = 67
char = P;code = 80
char = );code = 41
char = .;code = 46
char = ;code = 32
char = B;code = 66
char = e;code = 101
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char = a;code = 97
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char = s;code = 115
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char = t;code = 116
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char = e;code = 101
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char = m;code = 109
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char = c;code = 99
char = h;code = 104
char = o;code = 111
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char = d;code = 100
char = r;code = 114
char = i;code = 105
char = a;code = 97
char = l;code = 108
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char = c;code = 99
char = o;code = 111
char = n;code = 110
char = c;code = 99
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char = t;code = 116
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = U;code = 85
char = C;code = 67
char = P;code = 80
char = ,;code = 44
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char = r;code = 114
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char = l;code = 108
char = a;code = 97
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char = i;code = 105
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char = o;code = 111
char = ;code = 32
char = o;code = 111
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = r;code = 114
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char = m;code = 109
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char = t;code = 116
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char = c;code = 99
char = h;code = 104
char = o;code = 111
char = n;code = 110
char = d;code = 100
char = r;code = 114
char = i;code = 105
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = p;code = 112
char = r;code = 114
char = o;code = 111
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char = i;code = 105
char = n;code = 110
char = s;code = 115
char = ,;code = 44
char = ;code = 32
char = i;code = 105
char = s;code = 115
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char = n;code = 110
char = o;code = 111
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char = ;code = 32
char = a;code = 97
char = l;code = 108
char = t;code = 116
char = e;code = 101
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char = e;code = 101
char = d;code = 100
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char = i;code = 105
char = n;code = 110
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char = C;code = 67
char = a;code = 97
char = p;code = 112
char = -;code = 45
char = D;code = 68
char = e;code = 101
char = s;code = 115
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char = r;code = 114
char = a;code = 97
char = t;code = 116
char = s;code = 115
char = ,;code = 44
char = ;code = 32
char = i;code = 105
char = t;code = 116
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char = i;code = 105
char = s;code = 115
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char = c;code = 99
char = o;code = 111
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char = c;code = 99
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char = u;code = 117
char = d;code = 100
char = e;code = 101
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char = t;code = 116
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char = a;code = 97
char = t;code = 116
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char = m;code = 109
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char = s;code = 115
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
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char = m;code = 109
char = i;code = 105
char = t;code = 116
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char = c;code = 99
char = h;code = 104
char = o;code = 111
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char = d;code = 100
char = r;code = 114
char = i;code = 105
char = a;code = 97
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = B;code = 66
char = A;code = 65
char = T;code = 84
char = ;code = 32
char = o;code = 111
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char = ;code = 32
char = C;code = 67
char = a;code = 97
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char = e;code = 101
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char = r;code = 114
char = a;code = 97
char = t;code = 116
char = s;code = 115
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char = h;code = 104
char = a;code = 97
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char = e;code = 101
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char = b;code = 98
char = e;code = 101
char = e;code = 101
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char = l;code = 108
char = o;code = 111
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char = t;code = 116
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char = C;code = 67
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char = s;code = 115
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char = s;code = 115
char = t;code = 116
char = e;code = 101
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char = w;code = 119
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char = t;code = 116
char = h;code = 104
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char = t;code = 116
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char = s;code = 115
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char = i;code = 105
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char = z;code = 122
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char = C;code = 67
char = a;code = 97
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char = D;code = 68
char = e;code = 101
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char = r;code = 114
char = a;code = 97
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char = s;code = 115
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char = F;code = 70
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char = e;code = 101
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char = a;code = 97
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char = f;code = 102
char = f;code = 102
char = e;code = 101
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char = f;code = 102
char = e;code = 101
char = c;code = 99
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char = B;code = 66
char = A;code = 65
char = T;code = 84
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = C;code = 67
char = a;code = 97
char = p;code = 112
char = -;code = 45
char = D;code = 68
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = s;code = 115
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char = ;code = 32
char = F;code = 70
char = o;code = 111
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char = e;code = 101
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char = a;code = 97
char = k;code = 107
char = e;code = 101
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char = w;code = 119
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char = e;code = 101
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char = o;code = 111
char = r;code = 114
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char = a;code = 97
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char = i;code = 105
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char = C;code = 67
char = a;code = 97
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char = D;code = 68
char = e;code = 101
char = s;code = 115
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char = a;code = 97
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char = s;code = 115
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char = e;code = 101
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char = o;code = 111
char = s;code = 115
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char = e;code = 101
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char = C;code = 67
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char = f;code = 102
char = e;code = 101
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char = B;code = 66
char = A;code = 65
char = T;code = 84
char = ;code = 32
char = b;code = 98
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char = f;code = 102
char = f;code = 102
char = e;code = 101
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char = .;code = 46
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char = T;code = 84
char = h;code = 104
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char = e;code = 101
char = a;code = 97
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char = 5;code = 53
char = ';code = 39
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char = a;code = 97
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char = e;code = 101
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char = B;code = 66
char = A;code = 65
char = T;code = 84
char = ;code = 32
char = o;code = 111
char = c;code = 99
char = c;code = 99
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char = r;code = 114
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char = m;code = 109
char = a;code = 97
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char = l;code = 108
char = y;code = 121
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char = ;code = 32
char = C;code = 67
char = a;code = 97
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char = ;code = 32
char = p;code = 112
char = r;code = 114
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char = u;code = 117
char = m;code = 109
char = e;code = 101
char = d;code = 100
char = ;code = 32
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char = o;code = 111
char = ;code = 32
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char = e;code = 101
char = ;code = 32
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char = r;code = 114
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char = u;code = 117
char = g;code = 103
char = h;code = 104
char = t;code = 116
char = ;code = 32
char = a;code = 97
char = b;code = 98
char = o;code = 111
char = u;code = 117
char = t;code = 116
char = ;code = 32
char = b;code = 98
char = y;code = 121
char = ;code = 32
char = C;code = 67
char = a;code = 97
char = p;code = 112
char = -;code = 45
char = D;code = 68
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = u;code = 117
char = l;code = 108
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = e;code = 101
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = l;code = 108
char = o;code = 111
char = s;code = 115
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = t;code = 116
char = r;code = 114
char = o;code = 111
char = p;code = 112
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char = i;code = 105
char = c;code = 99
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = f;code = 102
char = l;code = 108
char = u;code = 117
char = e;code = 101
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = ;code = 32
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = m;code = 109
char = i;code = 105
char = t;code = 116
char = o;code = 111
char = c;code = 99
char = h;code = 104
char = o;code = 111
char = n;code = 110
char = d;code = 100
char = r;code = 114
char = i;code = 105
char = o;code = 111
char = g;code = 103
char = e;code = 101
char = n;code = 110
char = e;code = 101
char = s;code = 115
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = i;code = 105
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char = T;code = 84
char = ;code = 32
char = o;code = 111
char = r;code = 114
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = l;code = 108
char = a;code = 97
char = c;code = 99
char = k;code = 107
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = a;code = 97
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char = i;code = 105
char = b;code = 98
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char = t;code = 116
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char = r;code = 114
char = y;code = 121
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char = l;code = 108
char = u;code = 117
char = e;code = 101
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char = n;code = 110
char = ;code = 32
char = m;code = 109
char = i;code = 105
char = t;code = 116
char = o;code = 111
char = c;code = 99
char = h;code = 104
char = o;code = 111
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char = d;code = 100
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char = i;code = 105
char = a;code = 97
char = l;code = 108
char = ;code = 32
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char = k;code = 107
char = d;code = 100
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char = n;code = 110
char = ;code = 32
char = i;code = 105
char = n;code = 110
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char = ;code = 32
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char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
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char = ;code = 32
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result sql = Interscapular brown adipose tissue (BAT) of capsaicin-desensitized (Cap-Des) rats is atrophied, having a lower wet weight, a reduced total protein content, and as little as 10% of the normal content of uncoupling protein (UCP). Because the mitochondrial concentration of UCP, relative to other mitochondrial proteins, is not altered in Cap-Des rats, it is concluded that most of the mitochondria of BAT of Cap-Des rats have been lost. Consistent with this interpretation is a reduction of almost 40% of the overall thermogenic response to infused norepinephrine by anesthetized Cap-Des rats. Feeding a palatable diet had a delayed thermogenic effect and no trophic effect on BAT of Cap-Des rats. Food selection and intake were normal in Cap-Des rats, and diet-induced weight gain was the same as in control rats. Exposure of Cap-Des rats to cold for 1 or 7 days exerted a normal thermogenic effect on BAT but a delayed trophic effect. The cold-induced increase in thyroxine 5'-deiodinase in BAT occurred normally. Cap-Des rats were hypothermic at 1 day but normothermic by 7 days of cold exposure. The concentration of thyroid hormones in their blood was normal. It is suggested that the depletion of sensory neuropeptides in BAT presumed to be brought about by Cap-Des results either in loss of a trophic influence on mitochondriogenesis in BAT or in lack of an inhibitory influence on mitochondrial breakdown in BAT and leads to atrophy of BAT in rats living at 26 degrees C and an impaired response to stimulation by diet.(ABSTRACT TRUNCATED AT 250 WORDS)
Publication: Am. J. Physiol. 1990 Aug ;259(2 Pt 2)::R324-32.
Publication Date: 1990 Aug
Study Author(s): Cui, J;Zaror-Behrens, G;Himms-Hagen, J;
Institution: Department of Biochemistry, University of Ottawa Faculty of Medicine, Ontario, Canada.
Shortcut link to this study:
Publication Date: 1990 Aug
Study Author(s): Cui, J;Zaror-Behrens, G;Himms-Hagen, J;
Institution: Department of Biochemistry, University of Ottawa Faculty of Medicine, Ontario, Canada.
Shortcut link to this study:
Interscapular brown adipose tissue (BAT) of capsaicin-desensitized (Cap-Des) rats is atrophied, having a lower wet weight, a reduced total protein content, and as little as 10% of the normal content of uncoupling protein (UCP). Because the mitochondrial concentration of UCP, relative to other mitochondrial proteins, is not altered in Cap-Des rats, it is concluded that most of the mitochondria of BAT of Cap-Des rats have been lost. Consistent with this interpretation is a reduction of almost 40% of the overall thermogenic response to infused norepinephrine by anesthetized Cap-Des rats. Feeding a palatable diet had a delayed thermogenic effect and no trophic effect on BAT of Cap-Des rats. Food selection and intake were normal in Cap-Des rats, and diet-induced weight gain was the same as in control rats. Exposure of Cap-Des rats to cold for 1 or 7 days exerted a normal thermogenic effect on BAT but a delayed trophic effect. The cold-induced increase in thyroxine 5'-deiodinase in BAT occurred normally. Cap-Des rats were hypothermic at 1 day but normothermic by 7 days of cold exposure. The concentration of thyroid hormones in their blood was normal. It is suggested that the depletion of sensory neuropeptides in BAT presumed to be brought about by Cap-Des results either in loss of a trophic influence on mitochondriogenesis in BAT or in lack of an inhibitory influence on mitochondrial breakdown in BAT and leads to atrophy of BAT in rats living at 26 degrees C and an impaired response to stimulation by diet.(ABSTRACT TRUNCATED AT 250 WORDS)
PMID: 2386244
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