|
|
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result sql = Complementary and alternative medicine (CAM) use by patients enrolled in phase I clinical trials.
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char = a;code = 97
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char = l;code = 108
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char = C;code = 67
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char = u;code = 117
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char = a;code = 97
char = s;code = 115
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char = h;code = 104
char = i;code = 105
char = g;code = 103
char = h;code = 104
char = e;code = 101
char = r;code = 114
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char = a;code = 97
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char = a;code = 97
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char = e;code = 101
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char = t;code = 116
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char = a;code = 97
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char = m;code = 109
char = a;code = 97
char = l;code = 108
char = e;code = 101
char = s;code = 115
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char = 5;code = 53
char = 3;code = 51
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char = 5;code = 53
char = %;code = 37
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char = v;code = 118
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char = ;code = 32
char = 4;code = 52
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char = .;code = 46
char = 4;code = 52
char = %;code = 37
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char = .;code = 46
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char = V;code = 86
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char = t;code = 116
char = a;code = 97
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char = a;code = 97
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char = n;code = 110
char = e;code = 101
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char = a;code = 97
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char = s;code = 115
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char = p;code = 112
char = p;code = 112
char = l;code = 108
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char = m;code = 109
char = e;code = 101
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char = s;code = 115
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char = t;code = 116
char = a;code = 97
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char = i;code = 105
char = n;code = 110
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char = E;code = 69
char = ;code = 32
char = 4;code = 52
char = 8;code = 56
char = .;code = 46
char = 8;code = 56
char = %;code = 37
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char = t;code = 116
char = a;code = 97
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char = i;code = 105
char = n;code = 110
char = ;code = 32
char = C;code = 67
char = ;code = 32
char = 3;code = 51
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char = .;code = 46
char = 1;code = 49
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char = );code = 41
char = ;code = 32
char = c;code = 99
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char = s;code = 115
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char = t;code = 116
char = u;code = 117
char = t;code = 116
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = 8;code = 56
char = 9;code = 57
char = .;code = 46
char = 3;code = 51
char = %;code = 37
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = p;code = 112
char = h;code = 104
char = a;code = 97
char = r;code = 114
char = m;code = 109
char = a;code = 97
char = c;code = 99
char = o;code = 111
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char = o;code = 111
char = g;code = 103
char = i;code = 105
char = c;code = 99
char = ;code = 32
char = C;code = 67
char = A;code = 65
char = M;code = 77
char = ;code = 32
char = u;code = 117
char = s;code = 115
char = e;code = 101
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char = ;code = 32
char = 7;code = 55
char = 1;code = 49
char = .;code = 46
char = 4;code = 52
char = %;code = 37
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = e;code = 101
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char = t;code = 116
char = s;code = 115
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char = t;code = 116
char = o;code = 111
char = o;code = 111
char = k;code = 107
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char = n;code = 110
char = o;code = 111
char = n;code = 110
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char = t;code = 116
char = a;code = 97
char = m;code = 109
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char = n;code = 110
char = ,;code = 44
char = ;code = 32
char = n;code = 110
char = o;code = 111
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char = -;code = 45
char = m;code = 109
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char = n;code = 110
char = e;code = 101
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char = a;code = 97
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char = ;code = 32
char = p;code = 112
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char = a;code = 97
char = r;code = 114
char = m;code = 109
char = a;code = 97
char = c;code = 99
char = o;code = 111
char = l;code = 108
char = o;code = 111
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char = i;code = 105
char = c;code = 99
char = ;code = 32
char = C;code = 67
char = A;code = 65
char = M;code = 77
char = ;code = 32
char = p;code = 112
char = r;code = 114
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char = p;code = 112
char = a;code = 97
char = r;code = 114
char = a;code = 97
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char = i;code = 105
char = o;code = 111
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char = o;code = 111
char = f;code = 102
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char = w;code = 119
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char = i;code = 105
char = c;code = 99
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char = g;code = 103
char = r;code = 114
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char = e;code = 101
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char = t;code = 116
char = e;code = 101
char = a;code = 97
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char = (;code = 40
char = 2;code = 50
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char = 8;code = 56
char = %;code = 37
char = );code = 41
char = ,;code = 44
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char = e;code = 101
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char = i;code = 105
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char = a;code = 97
char = c;code = 99
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char = a;code = 97
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char = (;code = 40
char = 1;code = 49
char = 3;code = 51
char = .;code = 46
char = 1;code = 49
char = %;code = 37
char = );code = 41
char = ;code = 32
char = a;code = 97
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char = d;code = 100
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char = s;code = 115
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char = a;code = 97
char = c;code = 99
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char = (;code = 40
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char = 5;code = 53
char = %;code = 37
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char = w;code = 119
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char = r;code = 114
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char = s;code = 115
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char = u;code = 117
char = l;code = 108
char = a;code = 97
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char = .;code = 46
char = ;code = 32
char = S;code = 83
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char = i;code = 105
char = r;code = 114
char = i;code = 105
char = t;code = 116
char = u;code = 117
char = a;code = 97
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char = i;code = 105
char = t;code = 116
char = y;code = 121
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char = a;code = 97
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char = a;code = 97
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char = a;code = 97
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char = m;code = 109
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char = a;code = 97
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char = c;code = 99
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char = .;code = 46
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char = C;code = 67
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char = ;code = 32
char = C;code = 67
char = A;code = 65
char = M;code = 77
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char = u;code = 117
char = s;code = 115
char = e;code = 101
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char = s;code = 115
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char = I;code = 73
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char = T;code = 84
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char = o;code = 111
char = g;code = 103
char = e;code = 101
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char = .;code = 46
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result sql = 8053 Background: CAM usage among cancer patients is common, but usage in patients enrolled in phase I trials is unknown. There are potential pharmacologic interactions between CAM agents and experimental cancer therapies. This study describes the prevalence, clinical characteristics, and patterns of CAM use among patients enrolled in phase I trials.
Investigator-designed questionnaires were administered to 108 patients with advanced malignancies enrolled in phase I chemotherapy trials at Mayo Clinic. CAM was classified as pharmacologic and non-pharmacologic.
88.2% of respondents (90/102) used at least one CAM modality of whom 93.3% (84/90) used pharmacologic and 53.3% (48/90) used non-pharmacologic form of CAM. 46.7% (42/90) combined both approaches. 91.1% of CAM users had received prior standard chemotherapy. Overall, CAM use was higher among females than males (53.5% vs. 40.4%). Vitamin and mineral supplements (vitamin E 48.8%; vitamin C 38.1%) constituted 89.3% of pharmacologic CAM use. 71.4% of patients took non-vitamin, non-mineral pharmacologic CAM preparations of which green tea (29.8%), echinacea (13.1%) and essiac (9.5%) were the most popular. Spirituality (prayer and faith) was the most commonly practiced non-pharmacologic form of CAM, accounting for 52.1%. Chiropractors, the most frequently visited non-traditional medical practitioners, were consulted by only 10% of CAM users.
CAM use is widespread among phase I patients. This increases the potential for anti-cancer drug interactions with such CAM agents as green tea and echinacea which are known to affect hepatic drug metabolism. Essiac contains cytotoxic anthraquinones and other substances that interact with hormone receptors ( e.g. estrogen). Investigators should ascertain the CAM therapies utilized by patients as interactions between CAM agents and experimental agents can potentially lead to increased toxicity or alter efficacy of experimental drug therapy. No significant financial relationships to disclose.
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result sql = Complementary and alternative medicine (CAM) use by patients enrolled in phase I clinical trials.
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char = c;code = 99
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char = ;code = 32
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char = a;code = 97
char = t;code = 116
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = a;code = 97
char = c;code = 99
char = t;code = 116
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = h;code = 104
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char = r;code = 114
char = m;code = 109
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char = n;code = 110
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char = ;code = 32
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char = ;code = 32
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char = s;code = 115
char = t;code = 116
char = r;code = 114
char = o;code = 111
char = g;code = 103
char = e;code = 101
char = n;code = 110
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char = .;code = 46
char = ;code = 32
char = I;code = 73
char = n;code = 110
char = v;code = 118
char = e;code = 101
char = s;code = 115
char = t;code = 116
char = i;code = 105
char = g;code = 103
char = a;code = 97
char = t;code = 116
char = o;code = 111
char = r;code = 114
char = s;code = 115
char = ;code = 32
char = s;code = 115
char = h;code = 104
char = o;code = 111
char = u;code = 117
char = l;code = 108
char = d;code = 100
char = ;code = 32
char = a;code = 97
char = s;code = 115
char = c;code = 99
char = e;code = 101
char = r;code = 114
char = t;code = 116
char = a;code = 97
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = C;code = 67
char = A;code = 65
char = M;code = 77
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = a;code = 97
char = p;code = 112
char = i;code = 105
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = u;code = 117
char = t;code = 116
char = i;code = 105
char = l;code = 108
char = i;code = 105
char = z;code = 122
char = e;code = 101
char = d;code = 100
char = ;code = 32
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char = y;code = 121
char = ;code = 32
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char = e;code = 101
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char = ;code = 32
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char = n;code = 110
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char = a;code = 97
char = c;code = 99
char = t;code = 116
char = i;code = 105
char = o;code = 111
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char = e;code = 101
char = t;code = 116
char = w;code = 119
char = e;code = 101
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char = u;code = 117
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char = h;code = 104
char = e;code = 101
char = r;code = 114
char = a;code = 97
char = p;code = 112
char = y;code = 121
char = .;code = 46
char = ;code = 32
char = N;code = 78
char = o;code = 111
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = g;code = 103
char = n;code = 110
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
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char = o;code = 111
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char = h;code = 104
char = i;code = 105
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char = s;code = 115
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = d;code = 100
char = i;code = 105
char = s;code = 115
char = c;code = 99
char = l;code = 108
char = o;code = 111
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char = .;code = 46
char = <;code = 60
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result sql = 8053 Background: CAM usage among cancer patients is common, but usage in patients enrolled in phase I trials is unknown. There are potential pharmacologic interactions between CAM agents and experimental cancer therapies. This study describes the prevalence, clinical characteristics, and patterns of CAM use among patients enrolled in phase I trials.
Investigator-designed questionnaires were administered to 108 patients with advanced malignancies enrolled in phase I chemotherapy trials at Mayo Clinic. CAM was classified as pharmacologic and non-pharmacologic.
88.2% of respondents (90/102) used at least one CAM modality of whom 93.3% (84/90) used pharmacologic and 53.3% (48/90) used non-pharmacologic form of CAM. 46.7% (42/90) combined both approaches. 91.1% of CAM users had received prior standard chemotherapy. Overall, CAM use was higher among females than males (53.5% vs. 40.4%). Vitamin and mineral supplements (vitamin E 48.8%; vitamin C 38.1%) constituted 89.3% of pharmacologic CAM use. 71.4% of patients took non-vitamin, non-mineral pharmacologic CAM preparations of which green tea (29.8%), echinacea (13.1%) and essiac (9.5%) were the most popular. Spirituality (prayer and faith) was the most commonly practiced non-pharmacologic form of CAM, accounting for 52.1%. Chiropractors, the most frequently visited non-traditional medical practitioners, were consulted by only 10% of CAM users.
CAM use is widespread among phase I patients. This increases the potential for anti-cancer drug interactions with such CAM agents as green tea and echinacea which are known to affect hepatic drug metabolism. Essiac contains cytotoxic anthraquinones and other substances that interact with hormone receptors ( e.g. estrogen). Investigators should ascertain the CAM therapies utilized by patients as interactions between CAM agents and experimental agents can potentially lead to increased toxicity or alter efficacy of experimental drug therapy. No significant financial relationships to disclose.
Publication: J. Clin. Oncol. 2004 Jul;22(14_suppl):8053.
Publication Date: Jul 2004
Study Author(s): Mandrekar S S ; Dy G K GK ; Furth A A ; Bekele L L ; Hanson L L ; Sloan J J ; Adjei A A AA ;
Institution: Mayo Clinic College of Medicine, Rochester, MN.
Shortcut link to this study:
Publication Date: Jul 2004
Study Author(s): Mandrekar S S ; Dy G K GK ; Furth A A ; Bekele L L ; Hanson L L ; Sloan J J ; Adjei A A AA ;
Institution: Mayo Clinic College of Medicine, Rochester, MN.
Shortcut link to this study:
8053 Background: CAM usage among cancer patients is common, but usage in patients enrolled in phase I trials is unknown. There are potential pharmacologic interactions between CAM agents and experimental cancer therapies. This study describes the prevalence, clinical characteristics, and patterns of CAM use among patients enrolled in phase I trials.
Investigator-designed questionnaires were administered to 108 patients with advanced malignancies enrolled in phase I chemotherapy trials at Mayo Clinic. CAM was classified as pharmacologic and non-pharmacologic.
88.2% of respondents (90/102) used at least one CAM modality of whom 93.3% (84/90) used pharmacologic and 53.3% (48/90) used non-pharmacologic form of CAM. 46.7% (42/90) combined both approaches. 91.1% of CAM users had received prior standard chemotherapy. Overall, CAM use was higher among females than males (53.5% vs. 40.4%). Vitamin and mineral supplements (vitamin E 48.8%; vitamin C 38.1%) constituted 89.3% of pharmacologic CAM use. 71.4% of patients took non-vitamin, non-mineral pharmacologic CAM preparations of which green tea (29.8%), echinacea (13.1%) and essiac (9.5%) were the most popular. Spirituality (prayer and faith) was the most commonly practiced non-pharmacologic form of CAM, accounting for 52.1%. Chiropractors, the most frequently visited non-traditional medical practitioners, were consulted by only 10% of CAM users.
CAM use is widespread among phase I patients. This increases the potential for anti-cancer drug interactions with such CAM agents as green tea and echinacea which are known to affect hepatic drug metabolism. Essiac contains cytotoxic anthraquinones and other substances that interact with hormone receptors ( e.g. estrogen). Investigators should ascertain the CAM therapies utilized by patients as interactions between CAM agents and experimental agents can potentially lead to increased toxicity or alter efficacy of experimental drug therapy. No significant financial relationships to disclose.
Investigator-designed questionnaires were administered to 108 patients with advanced malignancies enrolled in phase I chemotherapy trials at Mayo Clinic. CAM was classified as pharmacologic and non-pharmacologic.
88.2% of respondents (90/102) used at least one CAM modality of whom 93.3% (84/90) used pharmacologic and 53.3% (48/90) used non-pharmacologic form of CAM. 46.7% (42/90) combined both approaches. 91.1% of CAM users had received prior standard chemotherapy. Overall, CAM use was higher among females than males (53.5% vs. 40.4%). Vitamin and mineral supplements (vitamin E 48.8%; vitamin C 38.1%) constituted 89.3% of pharmacologic CAM use. 71.4% of patients took non-vitamin, non-mineral pharmacologic CAM preparations of which green tea (29.8%), echinacea (13.1%) and essiac (9.5%) were the most popular. Spirituality (prayer and faith) was the most commonly practiced non-pharmacologic form of CAM, accounting for 52.1%. Chiropractors, the most frequently visited non-traditional medical practitioners, were consulted by only 10% of CAM users.
CAM use is widespread among phase I patients. This increases the potential for anti-cancer drug interactions with such CAM agents as green tea and echinacea which are known to affect hepatic drug metabolism. Essiac contains cytotoxic anthraquinones and other substances that interact with hormone receptors ( e.g. estrogen). Investigators should ascertain the CAM therapies utilized by patients as interactions between CAM agents and experimental agents can potentially lead to increased toxicity or alter efficacy of experimental drug therapy. No significant financial relationships to disclose.
PMID: 28015843
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