|
|
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result sql = Role of oxyradicals in the inactivation of catalase by ozone.
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result sql = The antioxidant enzymes, catalase and superoxide dismutase, are inactivated upon exposure to ozone. In this study, the mechanism of this inactivation was examined using catalase as a model system. The data show that the inactivation of catalase is dependent on ozone concentration, time of exposure, and pH. Loss of catalase activity is accompanied with loss of the heme spectra. Tiron, desferal-Mn, trolox-c, and pyruvate protect the enzyme against ozone inactivation. SOD is less effective due to its inactivation by ozone. On the other hand, alcohols do not provide significant protection. The data suggest the possible involvement of superoxide radicals in the inactivation of catalase by ozone.
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result sql = Role of oxyradicals in the inactivation of catalase by ozone.
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char = ;code = 32
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char = s;code = 115
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char = o;code = 111
char = z;code = 122
char = o;code = 111
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = i;code = 105
char = n;code = 110
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char = c;code = 99
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char = u;code = 117
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char = a;code = 97
char = l;code = 108
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = b;code = 98
char = y;code = 121
char = ;code = 32
char = o;code = 111
char = z;code = 122
char = o;code = 111
char = n;code = 110
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result sql = The antioxidant enzymes, catalase and superoxide dismutase, are inactivated upon exposure to ozone. In this study, the mechanism of this inactivation was examined using catalase as a model system. The data show that the inactivation of catalase is dependent on ozone concentration, time of exposure, and pH. Loss of catalase activity is accompanied with loss of the heme spectra. Tiron, desferal-Mn, trolox-c, and pyruvate protect the enzyme against ozone inactivation. SOD is less effective due to its inactivation by ozone. On the other hand, alcohols do not provide significant protection. The data suggest the possible involvement of superoxide radicals in the inactivation of catalase by ozone.
Publication: Free Radic. Biol. Med. 1988 ;5(5-6)::305-12.
Publication Date: 1988
Study Author(s): Whiteside, C;Hassan, H M;
Institution: Department of Food Science, North Carolina State University, Raleigh 27695-7624.
Shortcut link to this study:
Publication Date: 1988
Study Author(s): Whiteside, C;Hassan, H M;
Institution: Department of Food Science, North Carolina State University, Raleigh 27695-7624.
Shortcut link to this study:
The antioxidant enzymes, catalase and superoxide dismutase, are inactivated upon exposure to ozone. In this study, the mechanism of this inactivation was examined using catalase as a model system. The data show that the inactivation of catalase is dependent on ozone concentration, time of exposure, and pH. Loss of catalase activity is accompanied with loss of the heme spectra. Tiron, desferal-Mn, trolox-c, and pyruvate protect the enzyme against ozone inactivation. SOD is less effective due to its inactivation by ozone. On the other hand, alcohols do not provide significant protection. The data suggest the possible involvement of superoxide radicals in the inactivation of catalase by ozone.
PMID: 3256529
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