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char = a;code = 97
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char = t;code = 116
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char = h;code = 104
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char = e;code = 101
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char = i;code = 105
char = o;code = 111
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char = a;code = 97
char = s;code = 115
char = .;code = 46
result sql = Continuous low dose rate brachytherapy with high activity iodine-125 seeds in the management of meningiomas.
Continuous low dose rate brachytherapy with high activity iodine-125 seeds in the management of meningiomas.
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char = h;code = 104
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char = s;code = 115
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char = i;code = 105
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = h;code = 104
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char = g;code = 103
char = h;code = 104
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char = a;code = 97
char = c;code = 99
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char = i;code = 105
char = v;code = 118
char = i;code = 105
char = t;code = 116
char = y;code = 121
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char = I;code = 73
char = -;code = 45
char = 1;code = 49
char = 2;code = 50
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char = e;code = 101
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char = s;code = 115
char = .;code = 46
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char = T;code = 84
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char = i;code = 105
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char = m;code = 109
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char = e;code = 101
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char = h;code = 104
char = i;code = 105
char = g;code = 103
char = h;code = 104
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char = i;code = 105
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char = y;code = 121
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char = I;code = 73
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char = 1;code = 49
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char = 5;code = 53
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char = s;code = 115
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char = e;code = 101
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char = .;code = 46
char = ;code = 32
char = T;code = 84
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = h;code = 104
char = y;code = 121
char = s;code = 115
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char = a;code = 97
char = l;code = 108
char = ;code = 32
char = c;code = 99
char = h;code = 104
char = a;code = 97
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char = a;code = 97
char = c;code = 99
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char = e;code = 101
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char = t;code = 116
char = i;code = 105
char = c;code = 99
char = s;code = 115
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char = o;code = 111
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char = ;code = 32
char = I;code = 73
char = -;code = 45
char = 1;code = 49
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char = 5;code = 53
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char = e;code = 101
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char = a;code = 97
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char = a;code = 97
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char = m;code = 109
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char = i;code = 105
char = m;code = 109
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char = m;code = 109
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char = m;code = 109
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char = g;code = 103
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char = n;code = 110
char = g;code = 103
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char = f;code = 102
char = r;code = 114
char = o;code = 111
char = m;code = 109
char = ;code = 32
char = 1;code = 49
char = 0;code = 48
char = 0;code = 48
char = ;code = 32
char = G;code = 71
char = y;code = 121
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = 5;code = 53
char = 0;code = 48
char = 0;code = 48
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char = ;code = 32
char = a;code = 97
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char = ;code = 32
char = d;code = 100
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char = a;code = 97
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char = e;code = 101
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char = ;code = 32
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char = c;code = 99
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char = o;code = 111
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char = 2;code = 50
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char = ;code = 32
char = c;code = 99
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char = h;code = 104
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char = .;code = 46
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char = c;code = 99
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char = t;code = 116
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char = .;code = 46
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char = o;code = 111
char = f;code = 102
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char = ;code = 32
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char = d;code = 100
char = ;code = 32
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char = t;code = 116
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = l;code = 108
char = a;code = 97
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char = ;code = 32
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char = l;code = 108
char = l;code = 108
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char = w;code = 119
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char = s;code = 115
char = ;code = 32
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char = r;code = 114
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char = ;code = 32
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char = s;code = 115
char = e;code = 101
char = r;code = 114
char = v;code = 118
char = e;code = 101
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char = ;code = 32
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char = e;code = 101
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = n;code = 110
char = c;code = 99
char = l;code = 108
char = u;code = 117
char = d;code = 100
char = e;code = 101
char = ;code = 32
char = f;code = 102
char = r;code = 114
char = o;code = 111
char = m;code = 109
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = i;code = 105
char = t;code = 116
char = i;code = 105
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = d;code = 100
char = a;code = 97
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char = ;code = 32
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char = o;code = 111
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char = e;code = 101
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char = a;code = 97
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char = ;code = 32
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char = a;code = 97
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char = d;code = 100
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char = ;code = 32
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char = i;code = 105
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char = a;code = 97
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char = ;code = 32
char = e;code = 101
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char = f;code = 102
char = e;code = 101
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char = i;code = 105
char = v;code = 118
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char = ,;code = 44
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char = l;code = 108
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char = ;code = 32
char = m;code = 109
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char = o;code = 111
char = d;code = 100
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = t;code = 116
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = b;code = 98
char = o;code = 111
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = c;code = 99
char = u;code = 117
char = r;code = 114
char = r;code = 114
char = e;code = 101
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char = t;code = 116
char = ;code = 32
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char = n;code = 110
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char = c;code = 99
char = r;code = 114
char = a;code = 97
char = n;code = 110
char = i;code = 105
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = i;code = 105
char = o;code = 111
char = m;code = 109
char = a;code = 97
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result sql = The purpose of this study was to evaluate if meningiomas can be effectively treated with brachytherapy using permanent implantation of high activity I-125 seeds. Thirteen patients with intracranial meningiomas were treated by means of permanent stereotactic implantation of one or more high-activity I-125 seeds. The physical characteristics of I-125 enabled us to deliver a minimum tumor dose ranging from 100 Gy to 500 Gy at a low dose rate of 5 cGy to 25 cGy per hr. Indications for this procedure included recurrence after initial surgery or as primary modality of treatment in patients who were not candidates for surgery. All 13 patients are alive at a median follow-up of 25 months. Nine of 13 patients achieved complete resolution of the tumor and in the remaining four, more than 50% reduction in tumor volume was noted at the last follow-up. No late complications were observed. We conclude from this initial data that localized high dose irradiation delivered at a low dose rate using I-125 permanent implantation is an effective, safe, and simple method in the treatment of both recurrent and primary intracranial meningiomas.

Publication: Int. J. Radiat. Oncol. Biol. Phys. 1993 Jan 15 ;25(2)::325-8.
Publication Date: 1993 Jan 15
Study Author(s): Kumar, P P;Patil, A A;Leibrock, L G;Chu, W K;Syh, H W;McCaul, G F;Reeves, M A;
Institution: Division of Radiation Oncology, University of Nebraska Medical Center, Omaha 68198-1045.
Shortcut link to this study:

The purpose of this study was to evaluate if meningiomas can be effectively treated with brachytherapy using permanent implantation of high activity I-125 seeds. Thirteen patients with intracranial meningiomas were treated by means of permanent stereotactic implantation of one or more high-activity I-125 seeds. The physical characteristics of I-125 enabled us to deliver a minimum tumor dose ranging from 100 Gy to 500 Gy at a low dose rate of 5 cGy to 25 cGy per hr. Indications for this procedure included recurrence after initial surgery or as primary modality of treatment in patients who were not candidates for surgery. All 13 patients are alive at a median follow-up of 25 months. Nine of 13 patients achieved complete resolution of the tumor and in the remaining four, more than 50% reduction in tumor volume was noted at the last follow-up. No late complications were observed. We conclude from this initial data that localized high dose irradiation delivered at a low dose rate using I-125 permanent implantation is an effective, safe, and simple method in the treatment of both recurrent and primary intracranial meningiomas.

PMID: 8420881

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