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char = l;code = 108
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char = n;code = 110
char = a;code = 97
char = l;code = 108
char = y;code = 121
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char = s;code = 115
char = ;code = 32
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char = p;code = 112
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char = d;code = 100
char = a;code = 97
char = t;code = 116
char = a;code = 97
char = .;code = 46
result sql = Word reading in Alzheimer's disease: cross-sectional and longitudinal analyses of response time and accuracy data.
Word reading in Alzheimer's disease: cross-sectional and longitudinal analyses of response time and accuracy data.
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char = s;code = 115
char = ;code = 32
char = w;code = 119
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char = t;code = 116
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char = y;code = 121
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char = i;code = 105
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char = ;code = 32
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char = l;code = 108
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char = n;code = 110
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char = r;code = 114
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char = p;code = 112
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char = c;code = 99
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char = s;code = 115
char = ;code = 32
char = c;code = 99
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char = p;code = 112
char = r;code = 114
char = o;code = 111
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char = i;code = 105
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
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char = ;code = 32
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char = e;code = 101
char = ;code = 32
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char = e;code = 101
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = r;code = 114
char = o;code = 111
char = d;code = 100
char = u;code = 117
char = c;code = 99
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = g;code = 103
char = n;code = 110
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char = f;code = 102
char = i;code = 105
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char = a;code = 97
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char = ;code = 32
char = d;code = 100
char = e;code = 101
char = t;code = 116
char = e;code = 101
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char = o;code = 111
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char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
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char = f;code = 102
char = ;code = 32
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char = c;code = 99
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char = e;code = 101
char = m;code = 109
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char = ;code = 32
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char = s;code = 115
char = e;code = 101
char = ;code = 32
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char = e;code = 101
char = s;code = 115
char = u;code = 117
char = l;code = 108
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char = s;code = 115
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char = ;code = 32
char = r;code = 114
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char = l;code = 108
char = e;code = 101
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char = a;code = 97
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char = t;code = 116
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = c;code = 99
char = u;code = 117
char = r;code = 114
char = r;code = 114
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = o;code = 111
char = r;code = 114
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char = e;code = 101
char = s;code = 115
char = ;code = 32
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char = t;code = 116
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char = o;code = 111
char = r;code = 114
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char = ;code = 32
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char = ;code = 32
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char = m;code = 109
char = p;code = 112
char = a;code = 97
char = i;code = 105
char = r;code = 114
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = d;code = 100
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = p;code = 112
char = r;code = 114
char = o;code = 111
char = c;code = 99
char = e;code = 101
char = s;code = 115
char = s;code = 115
char = e;code = 101
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result sql = Using a list of high- and low-frequency regular and exception words, we measured the reading performance of three groups of subjects: patients with mild dementia of the Alzheimer's type (DAT) at presentation (Stage 1) and 2-3 years later (Stage 2); moderately severe DAT patients; and control subjects. In the longitudinally studied patients, there was a dramatic increase in response times (RTs) from Stage 1 to Stage 2, but little change in either error rate or pattern. By contrast, a comparison of the Stage 2 with the Moderate patients revealed similar RTs but a significant increase in error rate for the Moderate group, particularly on low-frequency exception words. These two results for word naming were almost exactly mirrored by effects in picture naming. We conclude that correct word reading, especially for less common words with atypical spelling-sound correspondences, is compromised in DAT only when the disease produces a significant deterioration of semantic memory. These results are relevant to current theories about normal and impaired reading processes.

Publication: Neuropsychologia 1998 Feb ;36(2)::155-71.
Publication Date: 1998 Feb
Study Author(s): Strain, E;Patterson, K;Graham, N;Hodges, J R;
Institution: MRC Applied Psychology Unit, Cambridge, UK.
Shortcut link to this study:
Using a list of high- and low-frequency regular and exception words, we measured the reading performance of three groups of subjects: patients with mild dementia of the Alzheimer's type (DAT) at presentation (Stage 1) and 2-3 years later (Stage 2); moderately severe DAT patients; and control subjects. In the longitudinally studied patients, there was a dramatic increase in response times (RTs) from Stage 1 to Stage 2, but little change in either error rate or pattern. By contrast, a comparison of the Stage 2 with the Moderate patients revealed similar RTs but a significant increase in error rate for the Moderate group, particularly on low-frequency exception words. These two results for word naming were almost exactly mirrored by effects in picture naming. We conclude that correct word reading, especially for less common words with atypical spelling-sound correspondences, is compromised in DAT only when the disease produces a significant deterioration of semantic memory. These results are relevant to current theories about normal and impaired reading processes.
PMID: 9539236

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