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SIRT1 Activator and Inflammatory
Silent information regulator, Sirtuin 1, and age-related diseases.
Geriatrics & gerontology international
A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Macrophage alpha1 AMP-activated protein kinase (alpha1AMPK) antagonizes fatty acid-induced inflammation through SIRT1.
The Journal of biological chemistry
SIRT1 modulates expression of matrix metalloproteinases in human dermal fibroblasts.
The British journal of dermatology
Anti-inflammatory effect of resveratrol on adipokine expression and secretion in human adipose tissue explants.
International journal of obesity (2005)
Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice.
American journal of physiology. Endocrinology and metabolism
Resveratrol exerts pharmacological preconditioning by activating PGC-1alpha.
Medical hypotheses
SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity.
American journal of physiology. Endocrinology and metabolism
Sirt1 acts in association with PPARα to protect the heart from hypertrophy, metabolic dysregulation, and inflammation.
Cardiovascular research
SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes.
Molecular and cellular biology
Role of FoxO1 in FFA-induced oxidative stress in adipocytes.
American journal of physiology. Endocrinology and metabolism
SIRT1 activation confers neuroprotection in experimental optic neuritis.
Investigative ophthalmology & visual science
Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein.
The Journal of biological chemistry
SIRT1 as a potential therapeutic target for treatment of nonalcoholic fatty liver disease.
Medical science monitor : international medical journal of experimental and clinical research
Resveratrol ameliorates muscular pathology in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy.
The Journal of pharmacology and experimental therapeutics
Resveratrol inhibits interleukin 1β-mediated inducible nitric oxide synthase expression in articular chondrocytes by activating SIRT1 and thereby suppressing nuclear factor-κB activity.
European journal of pharmacology
Activation of Sirt1 by resveratrol inhibits TNF-α induced inflammation in fibroblasts.
PloS one
Sirt1 overexpression protects murine osteoblasts against TNF-α-induced injury in vitro by suppressing the NF-κB signaling pathway.
Acta pharmacologica Sinica
Acute resveratrol treatment modulates multiple signaling pathways in the ischemic brain.
Neurochemical research
Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice.
Nutrition & metabolism
Geriatrics & gerontology international
A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Macrophage alpha1 AMP-activated protein kinase (alpha1AMPK) antagonizes fatty acid-induced inflammation through SIRT1.
The Journal of biological chemistry
SIRT1 modulates expression of matrix metalloproteinases in human dermal fibroblasts.
The British journal of dermatology
Anti-inflammatory effect of resveratrol on adipokine expression and secretion in human adipose tissue explants.
International journal of obesity (2005)
Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice.
American journal of physiology. Endocrinology and metabolism
Resveratrol exerts pharmacological preconditioning by activating PGC-1alpha.
Medical hypotheses
SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity.
American journal of physiology. Endocrinology and metabolism
Sirt1 acts in association with PPARα to protect the heart from hypertrophy, metabolic dysregulation, and inflammation.
Cardiovascular research
SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes.
Molecular and cellular biology
Role of FoxO1 in FFA-induced oxidative stress in adipocytes.
American journal of physiology. Endocrinology and metabolism
SIRT1 activation confers neuroprotection in experimental optic neuritis.
Investigative ophthalmology & visual science
Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein.
The Journal of biological chemistry
SIRT1 as a potential therapeutic target for treatment of nonalcoholic fatty liver disease.
Medical science monitor : international medical journal of experimental and clinical research
Resveratrol ameliorates muscular pathology in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy.
The Journal of pharmacology and experimental therapeutics
Resveratrol inhibits interleukin 1β-mediated inducible nitric oxide synthase expression in articular chondrocytes by activating SIRT1 and thereby suppressing nuclear factor-κB activity.
European journal of pharmacology
Activation of Sirt1 by resveratrol inhibits TNF-α induced inflammation in fibroblasts.
PloS one
Sirt1 overexpression protects murine osteoblasts against TNF-α-induced injury in vitro by suppressing the NF-κB signaling pathway.
Acta pharmacologica Sinica
Acute resveratrol treatment modulates multiple signaling pathways in the ischemic brain.
Neurochemical research
Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice.
Nutrition & metabolism
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How is this determined?
The order of these related concepts is determined by a statistical analysis of the scientific literature. Highest-frequency concepts appear first.
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Resveratrol 113 Glucose 37 Inflammatory 36 Nicotinamide 36 Insulin 33 Calorie 25 oxidative stress 23 Tumor 20 adenine 19 Fat 18 Nicotinamide adenine dinucleotide 17 Enzymes 16 cancer 16 lysine 15 Death 15 diabetes 15 Apoptotic 15 Cardiovascular 14 Toxicity 14 neurons 12 Superoxide dismutase 12 Obesity 12 Insulin Resistance 11 Neuroprotective 11 blood 8 Exercise 8 |
heart 8 Metabolic disorders 8 Hematopoietic 8 Cytotoxicity 8 lead 7 prostate 7 colon cancer 7 Oxidant 7 hepatitis 6 breast cancer 6 Fatty Acid Oxidation 6 Serine 6 Cardiomyopathy 6 Cardiovascular disease 6 radiation 5 Cholesterol 5 skin 5 Neurogenesis 5 Arginine 5 Antioxidants 5 liver cancer 5 Dopamine 5 alzheimer's 5 Manganese 5 Hepatitis B 5 |
